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Cleft Lip clinical trials

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NCT ID: NCT04369638 Terminated - Clinical trials for Cleft Lip and Palate

Fabrication of Naso-alveolar Molding (NAM) Appliance in Cleft Lip and Palate (CLP) From Digital Magnetic Resonance Imaging (MRI) Face Scan

Start date: January 27, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to fabricate a nasoalveolar molding (NAM) appliance that is digitally fabricated and 3 dimensionally printed utilizing an MRI face scan and to assess the fit of the NAM in new borns with cleft lip and palate.

NCT ID: NCT03740841 Terminated - Clinical trials for Cleft Lip and Palate

Evaluation of the Effects of LUNII on Pre-operative Anxiety and on the Post-operative Period in Children With Cleft Lip and Palate Admitted for Alveolar Bone Graft: Pilot Study

LUNII
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

The literature on the effects of various devices on per-operative anxiety is scarce. There is currently no study on the effects of an interactive storyteller on per-operative anxiety in pediatric surgery. The interactive story teller LUNII (available over the counter in France) would reduce pre-operative anxiety, with post-operative effects on pain and hospitalization time.

NCT ID: NCT03514563 Terminated - Clinical trials for Cleft Lip and Palate

Three Dimensional Facial Growth Analysis

Start date: June 1, 2018
Phase:
Study type: Observational [Patient Registry]

Cleft lip and palate is the most common facial birth defect affecting one in 700 babies, and frequently leads to problems in feeding, breathing, speech and/or hearing, and aesthetic problems often leading to social and psychological problems. Poor growth of the upper jaw affects nearly all patients with the condition, and can result in substantial misalignment of the teeth requiring corrective surgery and associated dental treatment in early adulthood. Surprisingly there is little evidence to support the current practice of delaying surgery until early adulthood. It is apparently left until then because it is assumed this is when the skull and face have stopped growing, but there is little available information on that growth and when the different parts of the face and skull stop growing. The goal of this study is to develop and test new computer-based methods to quantify skull growth and related soft- tissues changes. This pilot work will demonstrate whether it is possible to measure these developments and prepare the tools for a larger clinical study. That clinical study will determine the full nature and extent of bone growth and related soft-tissue changes during late adolescence, to identify if/when earlier surgery could be carried out to correct any deformity and minimise the associated social stigmas of the condition.

NCT ID: NCT02958306 Terminated - Clinical trials for Unilateral Cleft Lip

Effect of Platelet Rich Plasma (PRP) on the Esthetic Outcome and Scar Formation of Unilateral Cleft Lip Repair

Start date: December 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate effect of platelet rich plasma on scar formation of unilateral cleft lip repair.

NCT ID: NCT00213889 Terminated - Cleft Lip Clinical Trials

TWIST Human Gene and Cleft Lips and Palates

Start date: February 2003
Phase: N/A
Study type: Interventional

This study uses a sequence analysis for TWIST and other craniofacial development genes, among patients presenting with facial clefting.