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Cleft Lip clinical trials

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NCT ID: NCT05009472 Recruiting - Clinical trials for Cleft Lip and Palate

Rapid Maxillary Expansion and Protraction by Expander Differential Opening EDO in Cleft Lip and Palate Patients

Start date: June 26, 2021
Phase: N/A
Study type: Interventional

maxillary expansion in cleft palate patient with expander and using face mask.

NCT ID: NCT05002920 Completed - Clinical trials for Cleft Lip and Palate

Correlation Between Body Mass Index and Progressive Grafted Bone in Cleft Patients

Start date: January 25, 2021
Phase:
Study type: Observational

The cleft patients received alveolar bone graft(ABG) for alveolar defect. Body mass index (BMI) was measured for each patients when receiving ABG. Bone mineral density was measured by Cone-Beam CT at two time-points: post-ABG six months, and post-ABG two years. The study was to analyze the correlation between BMI and post-operative bone mineral density.

NCT ID: NCT04997083 Recruiting - Clinical trials for Cleft Lip and Palate

Slow Expansion and Protraction in Cleft Lip and Palate Patients

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

Evaluate the treatment outcome of slow maxillary expansion protocol on patients with cleft lip and palate, using a differential opening expander and face mask which will be measured and recorded by cone beam computed tomography (CBCT).

NCT ID: NCT04987190 Completed - Clinical trials for Cleft Lip and Palate

Progression of Grafted Bone Density in Cleft Alveolus

CDAABG
Start date: January 25, 2021
Phase:
Study type: Observational

The patients with unilateral and bilateral cleft lip and palate received alveolar bone graft surgery. Two time points of cone beam CT were taken for all the patients: post-operative 6 months, and post-operative 2 years. All the CT images were reviewed for the analysis of grafted bone density.

NCT ID: NCT04972370 Completed - Clinical trials for Patients With Unilateral Cleft Lip With or Without Cleft Palate

A Proposal for a New Classification of Secondary Cleft Lip and Nose Deformities in Repaired Unilateral Cleft Lip

Start date: January 1, 2006
Phase:
Study type: Observational

Congenital cleft lip with or without cleft palate is one of the most common congenital malformations with an estimated incidence of about 1 every 500 to 700 live births. Cleft lip and palate are caused by a complex combination of many environmental and genetic factors sharing into the etiology. Patients with cleft lip and palate undergo multiple surgeries to reconstruct the anatomy and function to achieve symmetric, aesthetic, and functional nasolabial region. The most important goals of correction of the cleft are to achieve an acceptable facial appearance and psychological and social well-being for the patient and his or her family. Therefore, assessment of nasolabial appearance following cleft surgery remains an important parameter for evaluating the outcome of the procedure. Unfortunately, some residual deformities in the nasolabial region such as the abnormal shape of the nose, scar of the upper lip, uneven white roll, notched or excess vermilion border will remain noticeable. So, the assessment of secondary cleft nasolabial deformities needs a reliable rating scale. Although many scoring systems have been described in the literature, there is no globally accepted reliable one. A frequently used scoring system is the one proposed by Asher-McDade that uses frontal and lateral view masked prints of the nasolabial area. The use of three-dimensional (3D) imaging seems to be the most reliable in assessing cleft-related facial deformities. However, scoring based on two-dimensional (2D) photographs is easier to perform and more applicable in daily practice because all cleft patients are photographed during their treatment journey at predetermined intervals. Assessment of secondary nasolabial deformities in cleft patients in large numbers of patients helps compare the aesthetic results of the different treatment protocols and techniques.

NCT ID: NCT04970095 Recruiting - Clinical trials for Cleft Lip and Palate

Alt-RAMEC Expansion and Protraction by EDO in Cleft Lip and Palate Patient

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

Evaluate the treatment outcome of Alternate Rapid Maxillary Expansion and Constriction Alt-RAMEC protocol on patients with cleft lip and palate, using a differential opening expander and face mask which will be measured and recorded by cone beam computed tomography (CBCT).

NCT ID: NCT04966572 Recruiting - Clinical trials for Cleft Lip and Palate

Short Term Efficiency of Presurgical Vacuum Formed Nasoalveolar Molding Aligners in Infants With Bilateral Cleft Lip and Palate Compared With Grayson Acrylic Formed Nasoalveolar Molding Appliances.

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Newborns with bilateral cleft lip/ palate will be treated pre-surgically by either presurgical vacuum-formed nasoalveolar molding aligners VF (NAM) or conventional Grayson acrylic formed nasoalveolar molding appliances in order to evaluate their effect on the maxillary arch.

NCT ID: NCT04791813 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Assessment of Maxillary Arch Depth and Width in a Group of Surgically Repaired Unilateral Cleft Lip and Palate Children Versus Normal Children .

Start date: March 2022
Phase:
Study type: Observational

The aim of the present study is to determine the effect of surgically repaired UCLP on dental arch dimensions and the need for orthodontic intervention in comparison with other healthy children , the presence of dental anomalies and the best possible standards of care among this group of Egyptian children.

NCT ID: NCT04771156 Recruiting - Clinical trials for Cleft Lip and Palate

Ketorolac in Palatoplasty

Start date: September 17, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to see if the addition of IV Ketorolac to usual care multi-modal pain therapy compared to usual care will improve oral intake post-operatively

NCT ID: NCT04735237 Not yet recruiting - Clinical trials for Unilateral Cleft Lip

Philtrum Reconstruction Using Autogenous Fat Injection Versus a Surgical Repair in Secondary Unilateral Cleft Lip Revision

Start date: October 2021
Phase: N/A
Study type: Interventional

Two groups of patients with repaired unilateral cleft lip deformity having mild to moderate grooving and/or scarring of the philtral column and requiring a secondary cleft lip repair. - The first group will receive upper lip fat injections into the philtral column (and other areas of volume insufficiency if needed) after manual fat liposuction from the abdomen. - The second group will receive surgical lip revision with reconstruction of the orbicularis oris muscle using inverted horizontal mattress sutures for enhancement of the philtral ridge.