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Cleft Lip clinical trials

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NCT ID: NCT04987190 Completed - Clinical trials for Cleft Lip and Palate

Progression of Grafted Bone Density in Cleft Alveolus

CDAABG
Start date: January 25, 2021
Phase:
Study type: Observational

The patients with unilateral and bilateral cleft lip and palate received alveolar bone graft surgery. Two time points of cone beam CT were taken for all the patients: post-operative 6 months, and post-operative 2 years. All the CT images were reviewed for the analysis of grafted bone density.

NCT ID: NCT04972370 Completed - Clinical trials for Patients With Unilateral Cleft Lip With or Without Cleft Palate

A Proposal for a New Classification of Secondary Cleft Lip and Nose Deformities in Repaired Unilateral Cleft Lip

Start date: January 1, 2006
Phase:
Study type: Observational

Congenital cleft lip with or without cleft palate is one of the most common congenital malformations with an estimated incidence of about 1 every 500 to 700 live births. Cleft lip and palate are caused by a complex combination of many environmental and genetic factors sharing into the etiology. Patients with cleft lip and palate undergo multiple surgeries to reconstruct the anatomy and function to achieve symmetric, aesthetic, and functional nasolabial region. The most important goals of correction of the cleft are to achieve an acceptable facial appearance and psychological and social well-being for the patient and his or her family. Therefore, assessment of nasolabial appearance following cleft surgery remains an important parameter for evaluating the outcome of the procedure. Unfortunately, some residual deformities in the nasolabial region such as the abnormal shape of the nose, scar of the upper lip, uneven white roll, notched or excess vermilion border will remain noticeable. So, the assessment of secondary cleft nasolabial deformities needs a reliable rating scale. Although many scoring systems have been described in the literature, there is no globally accepted reliable one. A frequently used scoring system is the one proposed by Asher-McDade that uses frontal and lateral view masked prints of the nasolabial area. The use of three-dimensional (3D) imaging seems to be the most reliable in assessing cleft-related facial deformities. However, scoring based on two-dimensional (2D) photographs is easier to perform and more applicable in daily practice because all cleft patients are photographed during their treatment journey at predetermined intervals. Assessment of secondary nasolabial deformities in cleft patients in large numbers of patients helps compare the aesthetic results of the different treatment protocols and techniques.

NCT ID: NCT04725370 Completed - Clinical trials for Cleft Lip and Palate

Characterization of Cleft Lip and Palate Conditions in Guatemala

Start date: October 30, 2017
Phase:
Study type: Observational

The purpose of this study is to compare types of and risk factors for cleft lip and palate in a Guatemalan population to a United States population.

NCT ID: NCT04696237 Completed - Clinical trials for Cleft Lip and Palate

National Treatment Approach Versus Standardized Treatment Protocol to Manage Patients With Cleft Lip and Palate: a Cross Sectional Study

Start date: January 15, 2021
Phase:
Study type: Observational [Patient Registry]

The main objective of this study is to provide data about treatment protocols for CLP patients in Egypt, and compare it to the management protocol suggested by the ACPA.

NCT ID: NCT04616690 Completed - Clinical trials for Cleft Lip and Palate

Three-dimensional Cleft Lip and Palate Morphology Prior to One-stage Cleft Repair

Start date: December 7, 2020
Phase:
Study type: Observational [Patient Registry]

This is a prospective observational cohort study of consecutive patients with cleft lip and palate deformity undergoing cleft repair at the Institute of Mother and Child in Warsaw. Cleft morphology will be captured with photo and intraoral camera before routine surgery at around 8 months. Furthermore, wound healing at 3 months postoperative will be assessed.

NCT ID: NCT04607213 Completed - Clinical trials for Unilateral Cleft Lip

Effectiveness of Rotation-advancement and Straight-line Surgical Approaches in Repairing Unilateral Cleft Lip Defect

Start date: November 13, 2019
Phase: N/A
Study type: Interventional

compare different effects of Rotation-advancement based on the Millard technique and Straight-line based on Fisher modification as surgical approaches in repairing lip defect of unilateral cleft lip patients.

NCT ID: NCT04384276 Completed - Clinical trials for Cleft Lip and Palate

Weigh Easy: Simplifying Home Weight Monitoring for Infants

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

This single-site, experimental, pilot study in infants identified from 0 - 3 months of age who present to the Cleft and Craniofacial Clinic with a cleft lip and/or palate will compare weight outcomes of infants who used the Weigh Easy system to monitor weight and historical infants whose weights were monitored without the Weigh Easy system.

NCT ID: NCT04331977 Completed - Clinical trials for Cleft Lip and Palate

Effectiveness of Two Maxillary Expanders in Improving the Transverse Skeletal and Dental Dimensions in Patients With Cleft Lip and Palate

Start date: July 2, 2020
Phase: N/A
Study type: Interventional

This randomized controlled trial is designed to compare between quadlelix appliance vs hyrax expander regrading the their effectiveness in maxillary expansion in patients with cleft.

NCT ID: NCT04331379 Completed - Clinical trials for Cleft Lip and Palate

Effectiveness of Nasal-alar Elevator Combined With Taping Vs. Taping Alone on Improving the Nose Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate

Start date: July 9, 2020
Phase: N/A
Study type: Interventional

This randomized trial is designed to assess the effectiveness of nasal elevator as a presurgical infant orthopedics on improvement of nose esthetics vs taping alone.

NCT ID: NCT04277273 Completed - Cleft Palate Clinical Trials

Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris

PEC-PMF
Start date: November 13, 2020
Phase: N/A
Study type: Interventional

Patients treated with Maxillofacial Prosthesis have loss of maxillary and/or mandibular substances. Few data are available on quality of life of these patients and its association with some of their socio-demographic, medical and clinical characteristics.