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Cleft Lip clinical trials

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NCT ID: NCT06122805 Recruiting - Gingivitis Clinical Trials

Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery

Start date: March 11, 2024
Phase: N/A
Study type: Interventional

The study is a randomized clinical trial to compare the effectiveness of a dual light ultrasonic toothbrush on periodontal health in orthodontic patients undergoing surgery. Patients with cleft lip and palate undergo bone graft and orthognathic surgery. The study will compare the periodontal outcomes in patients who use these toothbrushes during the post-surgical period.

NCT ID: NCT06105099 Recruiting - Clinical trials for Cleft Lip and Palate

Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Speech therapy in children with a palate deals with two scientific challenges that will be addressed in this project. The first challenge is selecting the best speech approach for a child with a specific cleft speech characteristic (CSC). Many speech therapists use a 'one-size-fits-all' approach to treat compensatory CSCs resulting in poor short- and long-term speech outcomes. To increase the effectiveness and quality of cleft speech care, it is necessary to find the best match between a specific therapy and a given type of CSC. Therefore, this proposal will compare the effect of 3 different speech approaches on the speech and quality of life in Dutch speaking children with different types of CSCs. The second challenge is selecting the best speech approach to enhance long-term learning and transfer of newly established speech skills to untrained consonants. To date, research mainly focused on immediate therapy effects. It is unknown if permanent speech changes occur. Hence, this project will also investigate the short-term and long-term learning effects (retention and transfer) of the different speech approaches from the first objective. This proposal will improve evidence-based and patient-tailored cleft speech therapy.

NCT ID: NCT06075069 Completed - Clinical trials for Cleft Lip and Palate

Evaluation of the Effect of Prosthetic Management for Congenital Cleft Lip and Palate Infants on the Middle Ear Function

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Aim of the study was to evaluate the effect of feeding appliance for congenital cleft lip and palate infants on the middle ear function

NCT ID: NCT06067854 Active, not recruiting - Clinical trials for Perioperative Analgesia in Neonates

Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery

Start date: January 1, 2022
Phase:
Study type: Observational

In retrospective data search the investigators will identified the cumulative consumption of opioid analgesics during surgery and 24 hours after surgery in neonate with cleft lips who underwent primary cleft lip repair surgery.

NCT ID: NCT05971914 Active, not recruiting - Clinical trials for Cleft Lip and Palate

Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft

Start date: October 12, 2021
Phase: N/A
Study type: Interventional

The present study aims at clinical and radiographic evaluation of the safety and efficacy of Bonmaker ATB powder combined with a novel split thickness papilla curtain flap in the treatment of alveolar cleft defects.

NCT ID: NCT05940389 Not yet recruiting - Clinical trials for Unilateral Cleft Lip

Nasolabial Soft Tissue Esthetics and Maxillary Changes in Unilateral Cleft Lip and Palate Using PreSurgical Infant Orthopedics With Different Approaches

PSIO
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The nasal deformity is an abnormality in the appearance and structure of the nose in cleft patients having unilateral cleft lip and palate (UCLP). It involves the displacement of the lower lateral nasal cartilage, oblique and short columella, depressed dome, overhanging nostril apex, and deviated septum. Difficulty in breathing and smelling are the main problems of this deformity. Rhinoplasty for CLP patients is very complicated due to the complex nature of this type of deformity, especially in wide and bilateral cleft patients it is quite challenging.

NCT ID: NCT05929560 Completed - Clinical trials for Unilateral Complete Cleft Lip and Palate

Digital Impression in Neonates

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The goal of this [clinical trial] is to [explore the attitudes of guardians with different educational background regarding the technique of impression registration as well as the compliance to using feeding appliances ] in [neonates]. Researchers will compare [conventional impression technique to digital impression]

NCT ID: NCT05876169 Enrolling by invitation - Clinical trials for Cleft Lip and Palate

How Does Orthognathic Surgery Affect Jaw and Neck Motor Function?

Start date: September 6, 2022
Phase: N/A
Study type: Interventional

In a prospective longitudinal study design, details in jaw-neck kinematics and electromyography (EMG) activity changes in patients (women and men) referred for surgical correction of basal relations between the maxilla and mandible over time; pre-operative and during follow-up 8 weeks and 18 months after surgical correction will be evaluated. The results will contribute with novel insights on jaw-neck motor function before, in short- and long-term after the surgical process. We will have blinded evaluation of outcomes.

NCT ID: NCT05837780 Enrolling by invitation - Clinical trials for Unilateral Cleft Lip and Palate

Effect of Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients

Start date: January 3, 2023
Phase: N/A
Study type: Interventional

This study includes Three Dimensional Evaluation of Maxillary Arch Changes After Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients (Randomized Controlled Trial) Null hypothesis: there is no difference between using conventionally constructed nasoalveolar molding device and using digitally constructed nasoalveolar molding device

NCT ID: NCT05830006 Not yet recruiting - Cleft Lip and Nose Clinical Trials

Indications and Evaluation of Microfat Grafting in Cleft Lip Nasal Deformities

Start date: May 1, 2025
Phase: N/A
Study type: Interventional

Aim of the work: The study will be conducted to investigate the efficacy of microfat graftinig in cleft lip nasal deformities especially in young patients and those adults who don't need major correction after rhinoplasty.