Cleaning Product Causing Toxic Effect Clinical Trial
Official title:
Comparison of Antimicrobial Activity of AvenovaTM as a Sterile Skin Preparation in Humans
Aim 1: To determine in vivo capability of AvenovaTM against common cutaneous microbial biome
on human skin
Aim 2: To compare to povidone-iodine 5% solution, 4% chlorhexidine and isopropyl alcohol
against AvenovaTM as a sterile skin agent
A total of approximately 30 eligible participants will be identified with clinically-acquired
information by Dr. Wendy Lee, an oculoplastic surgeon and aesthetic treatment specialist at
Bascom Palmer Eye Institute, during regular clinic visits.
Part One: Patients will have their skin swabbed and then cultured for various skin flora
agents. The petri dish will then be swabbed with Avenova to see what percent of skin flora
microbe is killed.
Part Two: Patients will have their skin divided into 4 quadrants. The area will be
pre-swabbed to monitor microbe growth. Each of 4 quadrants will be cleansed for one minute
with AvenovaTM , povidone-iodine 5% solution, 4% chlorhexidine and isopropyl alcohol, then
swabbed to monitor for microbe growth.
The swabs will be placed in thioglycollate broth to monitor for bacterial growth. If growth
if observed in the thioglycollate, the samples will be cultured on blood agar plates and the
bacterial specie(s) identified.
;