Clinical Trials Logo

Cirrhosis clinical trials

View clinical trials related to Cirrhosis.

Filter by:

NCT ID: NCT02344823 Recruiting - Clinical trials for Erectile Dysfunction

Effect of Vardenafil on Erectile Dysfunction and Portal Hemodynamics in Patients With Liver Cirrhosis

Start date: June 2012
Phase: Phase 4
Study type: Interventional

The investigators want to analyze the effect of Vardenafil on Erectile Dysfunstion and portal hemodynamics in patients with liver cirrhosis.

NCT ID: NCT02256046 Recruiting - Cirrhosis Clinical Trials

Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices

Start date: August 2014
Phase: N/A
Study type: Interventional

Aim of this thesis is to predict the incidence of esophageal ulcer bleeding after endoscopic management of esophageal varices. This study will be in the department of Tropical Medicine and Infectious Diseases, Tanta University, in at least six months in the period from august 2014 to march 2015 or until the target number of patients reached whichever is longer.

NCT ID: NCT02238444 Recruiting - Hypertension Clinical Trials

Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy

ESWA
Start date: September 1, 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether Warfarin Anticoagulation are effective and safe in Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients with Hypersplenism after Laparoscopic Splenectomy.

NCT ID: NCT02190357 Recruiting - Cirrhosis Clinical Trials

Rifaximin Reduces the Complications of Decompensated Cirrhosis: a Randomized Controlled Trial

Start date: August 2014
Phase: Phase 4
Study type: Interventional

Cirrhotic patients are predisposed to intestinal dysmotility, bacterial overgrowth, and increased intestinal permeability all leading to an increase in bacterial translocation and increased endotoxemia. Rifaximin is an antibiotic that is virtually non-absorbed after oral administration and exhibits broad spectrum antimicrobial activity against both aerobic and anaerobic gram-positive and gram-negative microorganisms within the gastrointestinal tract. It has been suggested that oral prophylactic antibiotics or bowel decontamination might improve long-term outcomes in patients with cirrhosis. The aim of this study was to explore the effect of rifaximin on the complications of advanced cirrhosis.

NCT ID: NCT02184000 Recruiting - Cirrhosis Clinical Trials

The Role of Strain Elastography in Staging Liver Fibrosis

SELF
Start date: March 2014
Phase: N/A
Study type: Observational

AIM: To evaluate the role of Strain Elastography in the assessment of liver fibrosis in chronic hepatopathy

NCT ID: NCT02131831 Recruiting - Cirrhosis Clinical Trials

Telomeres Parameters in Cirrhosis

Start date: June 2014
Phase: N/A
Study type: Observational

There are several factors that influence telomere length in patients with cirrhosis, such as metabolic derangements and infectious etiologies, The aim of the study is to compare telomere length and other parameters related to genetic instability in telomere/ telomerase system, in peripheral blood lymphocytes in cirrhosis from different etiologies.

NCT ID: NCT02074280 Recruiting - Cirrhosis Clinical Trials

Rifaximin Predicts the Complications of Decompensated Cirrhosis

Start date: October 2013
Phase: Phase 4
Study type: Interventional

Cirrhotic patients are predisposed to intestinal dysmotility, bacterial overgrowth, and increased intestinal permeability all leading to an increase in bacterial translocation and increased endotoxemia. Rifaximin is an antibiotic that is virtually non-absorbed after oral administration and exhibits broad spectrum antimicrobial activity against both aerobic and anaerobic gram-positive and gram-negative microorganisms within the gastrointestinal tract. It has been suggested that oral prophylactic antibiotics or bowel decontamination might improve long-term outcomes in patients with cirrhosis. The aim of this study was to explore the suitable dose of rifaximin to alleviate endotoxemia and prevent the complications of advanced cirrhosis.

NCT ID: NCT01992978 Recruiting - Clinical trials for Hepatocellular Carcinoma

Radiofrequency-assisted Hepatectomy on the Outcomes of HCC Patients With Cirrhosis

Start date: November 2013
Phase: N/A
Study type: Interventional

Surgical resection is the most effective treatment of primary and secondary liver tumors. Technical innovations have mainly focused on minimizing bleeding during transection of the hepatic parenchyma because excessive hemorrhage and the need for blood transfusion are associated with increased postoperative morbidity and mortality. Recently,radiofrequency-assisted(RFA)hepatectomy has developed rapidly and gained widespread acceptance for the treatment of hepatocellular carcinomas(HCC),but its influence on the prognosis of HCC patients,especially for those with cirrhosis,is still controversial. Therefore, we design this prospective clinical trial to explore the effect of RFA hepatectomy versus the conventional hepatectomy on the outcomes of perioperative period and prognosis of HCC patients with cirrhosis.

NCT ID: NCT01948687 Recruiting - Cirrhosis Clinical Trials

Real Time Elastography in Liver Fibrosis

RT-ELASTO
Start date: August 2013
Phase: N/A
Study type: Observational

AIM To evaluate the role of real time elastography (ARFI and Hitachi elastography) in noninvasive diagnosis of liver fibrosis in patients with chronic hepatitis

NCT ID: NCT01863121 Recruiting - Cirrhosis Clinical Trials

Validation of Child-Turcotte-Pugh-Kumar (CTPK) Score in Predicting Short Term Mortality in Patients With Liver Cirrhosis

Start date: May 2013
Phase: N/A
Study type: Observational

The CTP score is one of the best proved severity score in predicting mortality in patients with cirrhosis. Portal hypertension and variceal bleed are significant causes of morbidity and mortality in patients with cirrhosis. The recently published CTPK score included variceal variceal bleed status to the CTP score which improved the accuracy of CTP score in predicting short term mortality. CTPK score needs prospective validation.