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Cirrhosis, Liver clinical trials

View clinical trials related to Cirrhosis, Liver.

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NCT ID: NCT05184283 Terminated - Clinical trials for Hepatocellular Carcinoma

Utilization of MAsS in Patients Undergoing LT for HCC

Start date: June 16, 2022
Phase:
Study type: Observational

The aim of this study is to determine the effects of liver transplantation and standard immunosuppression on body composition in patients with compensated cirrhosis and hepatocellular carcinoma.

NCT ID: NCT04311489 Terminated - Cirrhosis, Liver Clinical Trials

Refractory Ascites in Patients With Liver Cirrhosis, and the Potential Treatment With 48 Hours Infusion of Ularitide.

ULA04
Start date: August 1, 2020
Phase: Phase 2
Study type: Interventional

This clinical trial intends to investigate the safety, tolerability and efficacy of ularitide on the renal response in patients with liver cirrhosis and refractory ascites for a maximum exposure duration of 48 hours, through a randomized, placebo-controlled, double-blind, single-center trial.

NCT ID: NCT04175392 Terminated - Cirrhosis, Liver Clinical Trials

Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis

PRONE
Start date: January 12, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This study will evaluate the effect of probiotics, a beneficial intestinal bacteria supplement, if it will cause improvement of the non-alcoholic fatty liver disease (NAFLD) and or non-alcoholic steatohepatitis (NASH- an inflammation with concurrent fatty accumulation of the liver) as measured by transient elastography - an ultrasound of the liver that assess the elastic properties (density) and stiffness of the liver tissue. This study will enroll patients 18 years and older with diagnosis of NAFLD and or NASH.

NCT ID: NCT04155099 Terminated - Cirrhosis, Liver Clinical Trials

Investigational Microbiota Restoration Therapeutic for Hepatic Encephalopathy

Start date: March 1, 2021
Phase: Phase 2
Study type: Interventional

Individuals with cirrhosis are likely to develop overt hepatic encephalopathy for which diagnostic modalities and treatment options are limited. The purpose of this study is to determine if individuals with cirrhosis who experience hepatic encephalopathy would benefit from investigational microbiota restoration therapy due to their inherent cognitive alterations. Analysis for a correlation between changes in microbiome composition and specific blood biomarkers could allow for earlier diagnosis of HE which could then be treated earlier and with novel treatments.

NCT ID: NCT03800069 Terminated - Healthy Clinical Trials

Validation of Point of Care Liver Function Tests

Start date: December 3, 2018
Phase:
Study type: Observational

This study is testing the accuracy of a point of care device that tests liver function within 20 minutes. The target population will be any adult who had liver function tests ordered and to be drawn on the same day as enrollment.

NCT ID: NCT03658551 Terminated - Cirrhosis, Liver Clinical Trials

Intestinal Permeability in Patients With Liver Cirrhosis Using Confocal Endoscopy

CEDIP-LCI
Start date: August 1, 2017
Phase:
Study type: Observational

The CEDIP LCI study is intended to show the difference in intestinal permeability between compensated and decompensated liver cirrhosis by confocal endoscopy.