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Cicatrix clinical trials

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NCT ID: NCT04187586 Completed - Burn Scar Clinical Trials

Effect of Extracorporeal Shock Wave Therapy for Burn Scar Charateristics

Start date: December 10, 2019
Phase:
Study type: Observational

No study has investigated the effect of extracorporeal shock wave therapy (ESWT) on hypertrophic scar characteristics. Thus, this study aimed to ascertain the effects ESWT on burn scars. The investigators retrospectively reviewed burn patients who had undergone autologous split-thickness skin grafting (STSG) with same artificial dermis between January 2012 and September 2019.

NCT ID: NCT04176705 Completed - Burn Scar Clinical Trials

Fractional Ablative Laser Treatment for Skin Grafts

Start date: December 14, 2020
Phase: N/A
Study type: Interventional

Doctors and patients refer to all areas of skin changes from burn injury as burn scars. However, different areas of scars from burns can be treated differently. The burn scars that come from skin grafting surgery might be improved with laser treatment. The purpose of this study is to see if treating burn skin graft scars with a laser could make it better. Fractional Ablative Laser has been approved by the US Food and Drug Administration (FDA), but it has not been approved for use in the early stages of scar maturation and is considered investigational for this study.

NCT ID: NCT04169490 Completed - Scar Clinical Trials

"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"

Start date: February 7, 2019
Phase: N/A
Study type: Interventional

A Phase II prospective, randomized, double-blind, placebo controlled and comparative clinical study evaluating hydrogel scar-management modalities for effective management of hyperproliferative scars and keloids. This is a double-blinded study, which means that neither the evaluating physician nor the subject will know which treatment is administered. Group selection and assignment will be made at random, with a 2 in 5 chance of receiving a market-approved therapy, and 1 in 5 chance of receiving the placebo. Subjects assigned the placebo-moisturizer will receive a standard hypoallergenic dermatological hydrating cream base. Subjects assigned the silicone gel, will receive a commercially available, active comparator.

NCT ID: NCT04066946 Completed - Cicatrix Clinical Trials

Study for the Effects of Microcurrent Therapy on the Prevention and Healing of Brachioplasty Scars

Start date: March 3, 2020
Phase: N/A
Study type: Interventional

Prospective, single-centre two-arm randomized controlled trial. Both groups receive standard wound care + hydration. The intervention group also receives microcurrent therapy. Patients with surgical incisions from bilateral Brachioplasty procedures will be included in this study. One arm will be randomized in the intervention group and one arm in the control group. Objective and subjective outcomes are registered. The aim of this study is to investigate whether the outcomes of the patients of the intervention group differ significantly from the patients in the control group.

NCT ID: NCT03971968 Completed - Cicatrix Clinical Trials

Observational Study for the Long-Term Effects of a Dermal Substitute on Patients With Facial Burns.

Start date: January 31, 2019
Phase:
Study type: Observational

The aim of this observational study is to investigate the long-term (between 10-20 years) results for the surgical treatment of third degree burn injury in the face and/or the neck by means of Integra® Dermal Regeneration Template. This study is an observational case-control study. The healthy skin of a comparable and/or contralateral skin-site of the face/neck serves as a comparator. The population consists of human volunteers between 18 and 75 years old with third degree full thickness burn injuries in the face and/or neck, who underwent surgical treatment with IDRT between 1998 and 2008.

NCT ID: NCT03915847 Completed - Clinical trials for Cesarean, Residual Myometrial Thickness

Evaluation of Cesarean Scar After Three Different Uterine Closure Technis

Start date: April 16, 2019
Phase: N/A
Study type: Interventional

The study compares three techniques of uterine closure on myometrium thickness at the site of uterine scar of women who underwent repeated cesarean section. Cesarean scar will be evaluated by transvaginal ultrasound six months after cesarean.

NCT ID: NCT03887208 Completed - Scar Clinical Trials

Therapy of Scars and Cutis Laxa With Autologous Adipose Derived Mesenchymal Stem Cells

2ABC
Start date: January 31, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is to compare clinical outcomes of patients with large scars or Cutis laxa treated with injections of autologous stromal vascular fraction cells (SVF) and adipose-derived mesenchymal stem cells (ADSC).

NCT ID: NCT03880058 Completed - Scars Clinical Trials

Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance

Start date: March 3, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

Multicenter, double-blind study comparing SLI-F06 to vehicle formulation buffer for the improvement in scar appearance and wound strength in routine surgical excisions, as well as post-operative abdominoplasty scar appearance.

NCT ID: NCT03842644 Completed - Scar Clinical Trials

Postoperative Skin Surface Tension Relaxing in Prevention of Facial Surgical Skin Scarring

Start date: February 16, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of early postoperative skin surface reduction in improving scar formation after facial surgery.

NCT ID: NCT03821324 Completed - Acne Scars Clinical Trials

Clinical Evaluation of Fractional Radiofrequency for the Treatment Acne Scarring

Start date: December 11, 2018
Phase: N/A
Study type: Interventional

Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring. The study will evaluate the progress of 15 subjects requesting treatment of acne scarring. The study will involve three treatments on both sides of the face with 3-5 week intervals between each treatment. Subjects will be followed at 6 and 12 weeks after their last treatment. Analysis will be performed on all subjects who receive at least one treatment.