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Cicatrix clinical trials

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NCT ID: NCT05239351 Completed - Lipodystrophy Clinical Trials

Evaluating Performance and Safety of the Medical Device Jalucomplex in the Treatment of Facial and Neck Tissue Defects

Start date: March 7, 2022
Phase: N/A
Study type: Interventional

The Research Question of the present study is the following: in a population of men and women presenting facial and neck dermal tissue defects (scars, hypertrophic scars, depressed plaques, and lipodystrophy defects) will linear hyaluronic acid (Jalucomplex®) significantly decrease and / or improve their appearance, results observed after 4 and 8 weeks?

NCT ID: NCT05239156 Completed - Lipodystrophy Clinical Trials

Evaluating the Performance and Safety of the Medical Device Janesse in the Treatment of Facial Dermal Tissue Defects

Start date: March 14, 2022
Phase: N/A
Study type: Interventional

The Research Question of the present study is the following: in a population of men and women presenting facial dermal tissue defects (scars, depressed plaques, and lipodystrophy defects) will cross-linked hyaluronic acid (Janesse®) significantly decrease and / or improve the appearance of these defects, results observed after 4, 8 and 12 weeks?

NCT ID: NCT05036785 Completed - Clinical trials for Suture Related Complication

Timing of Suture Removal to Reduce Scarring in Skin Surgery

Start date: December 7, 2021
Phase: N/A
Study type: Interventional

This is a single centre prospective randomized assessor blinded parallel group feasibility study that will be undertaken in the Royal Devon and Exeter Dermatology department. The investigators will be looking at whether timing of percutaneous suture removal after skin surgery impacts on the incidence of suture marks and overall scar cosmesis.

NCT ID: NCT04951869 Completed - Clinical trials for Keloid Scar Following Surgery

: Protescal: Prevention of Hypertrophic Scar and Keloid Formation Post Caesarean Section

Start date: April 26, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This study aimed to evaluate the effectiveness of Protescal in preventing post caesarean section hypertrophic scar and keloid formation.

NCT ID: NCT04827680 Completed - Clinical trials for Acne Scars - Mixed Atrophic and Hypertrophic

Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring. The study will evaluate the progress of 20 subjects requesting treatment of acne scarring. The study will involve three treatments on both sides of the face with 3-5 week intervals between each treatment. Subjects will be followed at 6 and 12 weeks after their last treatment. Analysis will be performed on all subjects who receive at least one treatment.

NCT ID: NCT04825821 Completed - Clinical trials for Cesarean Section Complications

Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture

Start date: March 1, 2019
Phase:
Study type: Observational

Late sequelae of a cesarean section related to a uterine scar defects include gynecological symptoms and obstetric complications. The aim of this study was to evaluate the incidence and characteristics of cesarean scar defects after uterine closure by double-layer barbed suture.

NCT ID: NCT04707131 Completed - Cicatrix Clinical Trials

A Study of Single Ascending Dose of LEM-S401 in Healthy Participants

Start date: July 11, 2022
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to assess the safety and tolerability of single dose of LEM-S401 in healthy adult subjects.

NCT ID: NCT04619589 Completed - Hypertrophic Scar Clinical Trials

Characterization of Dyschromic Hypertrophic Scar

Start date: May 21, 2019
Phase:
Study type: Observational

Currently, there are limited prevention or treatments available for dyschromia in burn hypertrophic scars (HTSs). The limited available techniques involve transferring melanocytes from unaffected areas to the scar to adjust pigment. These techniques involve the creation of a donor site and do not utilize the cells that may already be present in scars. This study aims to confirm melanocyte presence in regions of hypo- and hyper- pigmented HTS. If melanocytes can be found in regions of hypopigmentation, these scars may be able to be treated in the future by pigmentation stimulators without the need for surgery. Additionally, if pigmentation specific molecules of interest can be found to be up-regulated in hyperpigmented scar, these may be able to be altered by a pharmacotherapy.

NCT ID: NCT04558944 Completed - Clinical trials for Cicatrix, Hypertrophic

The Effect of Extracorporeal Shock Wave Therapy in the Treatment of Post Burn Scars

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

A prospective, randomized, controlled study. The patients were divided into two groups with twenty patients per group. The control group received the standard treatment for postburn scars. The treatment group received the standard treatment and treatment of postburn scars with Extracorporeal Shock Wave Therapy 512 impulses of 0.15mJ/mm 2 in each session, twice per week for 4 weeks. The investigators assessed the appearance of scar with the Vancouver Scar Scale (VSS), pruritus and pain with Visual Analog Scale (VAS) before the start of the treatment and at 2 weeks and 5 months after the treatment.

NCT ID: NCT04490213 Completed - Clinical trials for Donor Site Complication

Scarring At Donor Sites After Split-Thickness Skin Graft.

Start date: June 15, 2018
Phase:
Study type: Observational

The aim of this study was to investigate if previous findings on the association between dressing treatments and subjective opinion on final donor site scar outcome using the patient scale of POSAS could be confirmed objectively. Scar outcome measurements were assessed by a blinded observer using POSAS and the device: Cutometer dual MPA 580 (Courage and Khazaka Electronic GmbH, Cologne, Germany) to measure the viscoelasticity of the skin.