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Cicatrix clinical trials

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NCT ID: NCT05166395 Withdrawn - Scar Clinical Trials

Laser Treated Scars and Optical Coherence Tomography (OCT)

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this research study is to learn about the effects of the 2940 nm Erbium: Yttrium-Aluminum-Garnet (Er:YAG) laser on treating surgical scar using optical coherence tomography, a medical imaging device.

NCT ID: NCT05123508 Withdrawn - Scars Clinical Trials

Treatment of Breast Lift/Reduction Scars

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

Laser and light treatment for surgical scars following breast lifts/reductions

NCT ID: NCT04269317 Withdrawn - Scars Clinical Trials

Clinical Study to Evaluate the Safety and Effectiveness of the Treatment With Tixel C on Acne Scars

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this research is to evaluate the safety and effectiveness of the Tixel C device for the treatment of acne scars, for improvement in the appearance of surface texture.

NCT ID: NCT04034615 Withdrawn - Cicatrix Clinical Trials

The Long-term Effect of Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars

Start date: May 20, 2021
Phase: Phase 2
Study type: Interventional

The study is to investigate the long-term efficacy of perinatal tissue mesenchyme stem cells treatment on the appearance of a caesarean scar as compared to a similar untreated scar.

NCT ID: NCT03395678 Withdrawn - Acne Vulgaris Clinical Trials

Acne Scarring in Skin of Color: Laser vs Microneedling

Start date: November 2019
Phase: N/A
Study type: Interventional

Atrophic acne scars are a common and important sequelae of acne that affect up to 43-55% of patients with acne. Scarring impacts quality of life with reports of diminished self-esteem and frustration/sadness; additionally, some individuals report that their appearance even interferes with their professional lives. Though many treatments for acne scarring exist including ablative and nonablative lasers, subcision, and peels, none is without risk of adverse effects of pain, post-procedure redness or pigmentary changes. There have been no randomized studies directly comparing the effectiveness and safety profiles of microneedling (Dermapen) to 1,540nm nonablative fractional lasers (Palomar StarLux) in the treatment of atrophic acne scarring in skin of color. This clinical trial aims to determine which treatment modality -- microneedling or nonablative fractional laser -- is safer and more efficacious in the treatment of acne scarring in patients with skin of color.

NCT ID: NCT03306628 Withdrawn - Skin Scarring Clinical Trials

Early Carbon Dioxide Laser Therapy for Alleviation of Incisional Scar Burden

Start date: November 15, 2017
Phase: N/A
Study type: Interventional

This is a prospective, randomized pilot study of patients who will undergo either early or late incisional laser therapy after breast reduction surgery to alleviate scar burden at NYU Langone Medical Center. The purpose of this study is to see how well carbon dioxide (CO2) laser therapy works at preventing scar formation after surgery.CO2 laser therapy is currently being used by dermatologists and plastic surgeons to help with scarring after acne and to rejuvenate the face; its benefits are now being explored by medical professionals in dermatology and cosmetic surgery to prevent scarring after surgery.

NCT ID: NCT03181087 Withdrawn - Uterine Scar Clinical Trials

Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars

Start date: December 11, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.

NCT ID: NCT02968459 Withdrawn - Uterine Scar Clinical Trials

Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars

Start date: October 2021
Phase: Phase 2
Study type: Interventional

This is a single center, randomized, double blind, placebo controlled study to evaluate the safety and efficacy of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of caesarean section uterine scars.

NCT ID: NCT02776618 Withdrawn - Clinical trials for Cosmetics, Suture, Cicatrix

Polyglactin 910 vs Poligelecaprone 25 Running Subcuticular Closure of Elliptical Excision Wounds

Start date: May 15, 2016
Phase: N/A
Study type: Interventional

We will be recruiting patients requiring excisions of skin cancer and comparing aesthetic and functional differences of suture repair of excisional defects using polyglactin 910 vs poliglecaprone 25 with a split-scar model. Excision sites will be on either the trunk or extremities. Standard dermatological excision and repair methods will be used for removal of lesions and repair of the wound by surgeons; training courses will be used to limit inter-surgeon variation in technique. Excisional defects will be repaired with deep polyglactin 910 sutures, followed by randomly assigned subcuticular closure of one half of the defect with polyglactin 910 sutures and the other half with poliglecaprone 25 sutures. The patient will follow-up at 6 months and fill out a patient self-assessment evaluation survey of the scar. Photographs will also be taken of the scars at the follow-up at 6 months, which will be then be assigned to a set of blinded observers to evaluate the wound using a modified Patient Observer Self-Assessment Scale (mPOSAS). These observers will rate each scar on the mPOSAS scale and values will be averaged between observers. Total duration of participation will be 6 months, with 2 total visits (excision visit and follow-up visit).

NCT ID: NCT01433198 Withdrawn - Burns Clinical Trials

Aquatic Training in Patients With Severe Scarring

Start date: May 2018
Phase: N/A
Study type: Interventional

Aim: - to investigate the effects of an aquatic exercise program in patients with severe scars Patient population: - 10 patients of at least 18 years old - patients with scars after burns or other severe skin injuries - stratification into two groups: an intervention group and a control group Method: - 8 patients will participate in the aquatic exercise group and 2 patients in the control group - assessment of physical fitness parameters, scar tissue and psychosocial impact Hypothesis: - patients of the aquatic exercise group will recover sooner and better (physically and psychologically) than patients of the control group