Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina — RENEW

Refractory Angina Pectoris Clinical Trial

Official title:
A Prospective, Randomized, Double-blinded, Active-control and Unblinded Standard of Care (SOC) Controlled Study to Determine the Efficacy and Safety of Targeted Intramyocardial Delivery of Autologous CD34+ Cells (Auto-CD34+ Cells) for Increasing Exercise Capacity During Standardized Exercise Testing in Subjects With Refractory Angina Pectoris and Chronic Myocardial Ischemia

Status Completed

Clinical Trial Summary

The purpose of the study is to assess the safety and efficacy of targeted intramyocardial delivery of Auto-CD34+ cells for increasing exercise time and amelioration of anginal symptoms in subjects with refractory angina and chronic myocardial ischemia.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01508910
Study type	Interventional
Source	Caladrius Biosciences, Inc.
Contact
Status	Completed
Phase	Phase 3
Start date	April 2012
Completion date	November 2015

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT03438500` - Cardiac Shock Wave Treatment in Patients With Reduced Coronary Flow Reserve	N/A
Recruiting	`NCT01711099` - Efficacy of Extracorporeal Shockwave Myocardial Revascularization	N/A
Active, not recruiting	`NCT03039751` - Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris	Phase 2
Suspended	`NCT01567592` - Extracorporeal Shockwave Therapy for the Treatment of Chronic Angina Pectoris	Phase 1
Recruiting	`NCT05711849` - Assessing the Safety and Effectiveness of Intracoronary Stem Cells in Patients With Refractory Angina	Phase 2
Active, not recruiting	`NCT01241968` - Extracorporeal Shock Wave Therapy for the Treatment of Ischemic Heart Disease	Phase 2
Recruiting	`NCT02499250` - Effect of Daily Remote Ischemic Conditioning on the Life Quality of Refractory Angina Pectoris Patients	N/A
Completed	`NCT01219218` - Extracorporeal Shockwave Therapy for the Treatment of Advanced Angina Pectoris	Phase 1
Active, not recruiting	`NCT01567644` - Extracorporeal Shockwave Therapy for the Treatment of Refractory Chronic Angina Pectoris	Phase 1
Completed	`NCT00662727` - Extracorporeal Shockwave Therapy for the Treatment of Refractory Angina Pectoris	Phase 2
Completed	`NCT04121845` - CoROnary SinuS Reducer implantatiOn for ischemiA reDuction	N/A
Active, not recruiting	`NCT05174572` - IMR Evaluation in Patients With Coronary Sinus Reducer Implantation (INROAD Study)	N/A
Recruiting	`NCT04915157` - Efficacy of Spinal Cord Stimulation in Patients With Refractory Angina Pectoris	N/A