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Chronic Kidney Disease clinical trials

View clinical trials related to Chronic Kidney Disease.

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NCT ID: NCT03387319 Completed - Clinical trials for Chronic Kidney Disease

Stress and CKD Among African Americans

Start date: April 27, 2018
Phase: N/A
Study type: Interventional

The goal of this study is to determine whether experiencing stress from discrimination may increase chronic kidney disease (CKD) progression in African Americans. Study participation occurs over the course of 2 days, and participant time burden is expected to be about 4.5 hours, plus a 24-hour period of wearing a blood pressure monitor.

NCT ID: NCT03377413 Completed - Clinical trials for Chronic Kidney Disease

Novel Equation for Estimating Resting Energy Expenditure

Start date: December 14, 2017
Phase:
Study type: Observational

The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations are not applicable to CKD patients,so we aim to develop and validate a equation for estimating resting energy expenditure in CKD patients.

NCT ID: NCT03367338 Completed - Hyperphosphatemia Clinical Trials

Low-Phosphate Diet and Fibroblast Growth Factor-23 Level

Start date: January 3, 2018
Phase: N/A
Study type: Interventional

The aims of the study are to evaluate the effect of low-phosphate diet on FGF23 level and to determine the optimal amount of dietary phosphate restriction in hemodialysis patients. In particular, the investigators will assess the comparing effect of pre-specified low-phosphate diets, very low-phosphate diet, phosphate-to-protein ratio (PPR) value of 8 mg/g, versus low-phosphate diet, PPR value of 10 mg/g, on the change of FGF23 and phosphate level.

NCT ID: NCT03354910 Completed - Clinical trials for Chronic Kidney Disease

House Calls and Peer Mentorship

HC+PM
Start date: April 30, 2018
Phase: N/A
Study type: Interventional

Live donor kidney transplantation (LDKT) offers the most optimal survival and quality of life benefit for those with late-stage chronic kidney disease. However, minorities, especially blacks, are much less likely to receive LDKT than whites. Given the shortage of deceased donor organs, interventions expanding access to LDKT are needed, particularly for minority patients. House Calls (HC), an educational intervention developed by this study's PI has been shown to be an effective program for raising rates of live donation, especially for black patients. While the HC program has shown outstanding results, participant feedback suggested that follow-up may provide even more benefits. Previous research suggests that peer mentorship (PM) from former or current patients with ESRD may be effective in raising rates of living donation. As such, peer mentorship programs may act as an effective follow-up for HC participants. This study will examine the impact of the HC intervention combined with the peer mentorship program of the National Kidney Foundation on rates of live donor kidney transplantation.

NCT ID: NCT03352895 Completed - Clinical trials for Chronic Kidney Disease

The Effects of Resveratrol on the Complications of Patients With Hemodialysis

Start date: November 2014
Phase: N/A
Study type: Interventional

Participants'll include 140 adult patients with CKD and receiving hemodialysis in our hospital, and divided them into 2 groups. Control group will receive placebo medication therapy; resveratrol group will receive oral resveratrol (100 mg per day). All participants will receive either treatment for 1year, and receive examinations of pure tone audiometry, speech reception thresholds, and speech discrimination score.

NCT ID: NCT03342183 Completed - Clinical trials for Chronic Kidney Disease

Reducing Hemodialysis Induced Recurrent Brain Injury to Improve Patients' Lives

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

Patients who receive dialysis for kidney failure suffer severe cognitive impairment. Hemodialysis causes circulatory stress and ischemia, which causes severe brain injury. It has been demonstrated that a procedure known as Remote Ischemic Preconditioning(RIPC), which involves wrapping a blood pressure cuff around a patient's leg and inflating has the potential of protecting many organs, such as the heart from the effects of dialysis. Our study aims to investigate this phenomenon to determine the extent to which it provides protection to a dialysis patient's brain.

NCT ID: NCT03299816 Completed - Hypertension Clinical Trials

Five, Plus Nuts and Beans for Kidneys

Start date: February 22, 2018
Phase: N/A
Study type: Interventional

This Five, Plus Nuts and Beans for Kidneys Study is a single center, randomized controlled trial with 2 parallel arms testing the hypothesis that delivery of nutritional advice to adopt a Dietary Approaches to Stop Hypertension (DASH)-like diet and $30/week worth of fruits, vegetables, nuts and beans tailored to personal choices and availability in neighborhood stores, will reduce kidney damage in African Americans with hypertension and chronic kidney disease.

NCT ID: NCT03299244 Completed - Clinical trials for Chronic Kidney Disease

Head-to-Head Study of Etelcalcetide and Cinacalcet in Asian Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT)

Start date: May 15, 2018
Phase: Phase 3
Study type: Interventional

The primary objective is to demonstrate that treatment with etelcalcetide (AMG 416) is not inferior to treatment with cinacalcet for lowering serum intact parathyroid hormone (PTH) levels by > 30% from baseline among participants with chronic kidney disease (CKD) and secondary hyperparathyroidism (SHPT) who require management with hemodialysis.

NCT ID: NCT03286712 Completed - Anemia Clinical Trials

The Effect on Vascular Reactivity Using the Erythropoeitin Alpha on Incident Peritoneal Dialysis Patients

Start date: October 2015
Phase: Phase 4
Study type: Interventional

This is a prospective observational study on incident peritoneal dialysis patients on the effect of hemoglobin level and vascular reactivity using the generic erythropoietin alpha. The objective of the study is to to describe the effect of improvement in hemoglobin level and the flow-mediated dilatation using Epoeitin Alpha (Renogen). Patients who will meet the inclusion and exclusion criteria will have their baseline laboratory test and ultrasound of the brachial artery to assess the flow mediated dilatation. This is a 3-month follow up study with a monthly laboratory test to monitor the patients. The following are the outcome measures: hemoglobin level, vascular reactivity by measuring the flow mediated dilatation of the brachial artery and blood pressure.

NCT ID: NCT03270956 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Study of Autologous Renal Autologous Cell Therapy (REACT) in Patients With Diabetic Chronic Kidney Disease

Start date: April 25, 2018
Phase: Phase 2
Study type: Interventional

The purpose of the present study is to assess the safety and efficacy of up to 2 injections of REACT given 6 months (+4 weeks) apart (maximum).