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Cholesteatoma clinical trials

View clinical trials related to Cholesteatoma.

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NCT ID: NCT06424704 Not yet recruiting - Clinical trials for Microbial Colonization

Chronic Suppurative Otitis Media Microbiology

Start date: May 15, 2024
Phase:
Study type: Observational [Patient Registry]

This study is planned to reveal the microbiological agents and drug sensitivities to these agents in patients diagnosed with chronic suppurative otitis media who complain of ear discharge.

NCT ID: NCT06268938 Active, not recruiting - Cholesteatoma Clinical Trials

Outcomes of Mastoid Obliteration Canal Wall Down Tympanomastoidectomy in Cholesteatoma Surgery

Start date: September 4, 2023
Phase: N/A
Study type: Interventional

Randomised study to evaluate the outcomes of mastoid cavity obliteration by muscle versus bone in canal wall down tympanomastoidectomy in cholesteatoma surgery

NCT ID: NCT06246682 Recruiting - Clinical trials for Cholesteatoma, Middle Ear

Impact of Mastoid Condition on Results of Endoscopic Management of Cholesteatoma

Start date: February 10, 2024
Phase: N/A
Study type: Interventional

The goal of this interventional study is to learn about the effect of mastoid process status and the method of ossicular reconstruction on the results of the procedure transcanal endoscopic management of patients with localized atticoantral cholesteatoma

NCT ID: NCT06016335 Completed - Hearing Loss Clinical Trials

MRI-based Synthetic CT Images of the Head and Neck

Start date: September 22, 2022
Phase: N/A
Study type: Interventional

In case of surgical procedures in the head and neck region, MRI in combination with CT of the bone is often the standard modality to visualise bony landmarks for planning, navigation and risk assessment. An important downside of a CT scan is the associated radiation exposure, especially in children. An additional downside is the sedation or general anaesthesia needed for both the MRI and CT scan session in very young children. These downsides could be removed if the CT scan can be substituted by an MRI sequence that can provide the same information as CT. This project aims to determine the feasibility of recreating CT like images of the craniofacial bones from MRI images using machine learning techniques.

NCT ID: NCT05921643 Recruiting - Cholesteatoma Clinical Trials

Short- and Medium-term Evaluation of Mastoid Filling Using Bioactive Glass"

GLASS-BONA
Start date: September 29, 2023
Phase:
Study type: Observational

Adult patients referred to the ENT surgery department of the Hospices Civils de Lyon with cholesteatoma that had never been operated on. All patients will benefit from surgical management for cholesteatoma initially in the operating room under general anesthesia. The surgical technique (closed technique) is the reference technique for the management of cholesteatoma in adults. It involves a cartilaginous removal to reconstruct the attical region. Then a filling material is used to fill the mastoid (GlassBONEā„¢ or Bonaliveā„¢), and above all to stabilize the cartilaginous fragment to prevent a recurrence.

NCT ID: NCT05584891 Not yet recruiting - Clinical trials for Paediatric Cholesteatoma

Radical Mastoidectomy Versus Mastoid Oblitration in Pediatric Population

Start date: June 30, 2023
Phase:
Study type: Observational

Chronic otitis media (COM) has a significant impact on health issues since prehistoric time. It is a global disease, seen in all the continents of world having different environmental and socioeconomic background. COM is characterized as a permanent abnormality of the pars tensa or flaccida, most likely a result of earlier acute otitis media, negative middle ear pressure or otitis media with effusion. COM squamous active (cholesteatoma) is a type of COM, which is a mass formed by keratinizing squamous epithelium in the middle ear and/or mastoid, subepithelial connective tissue and by the progressive accumulation of keratin debris with/without surrounding inflammatory reaction.

NCT ID: NCT05182268 Completed - Clinical trials for Endoscopy; Microscopy; Ear Surgery; Cholesteatoma; Clinical Effect

Comparison of Clinical Effect Between Endoscopic and Microscopic Ear Surgery of Cholesteatoma: A Multicenter Retrospective Observational Study

Start date: November 1, 2016
Phase:
Study type: Observational

Background: Cholesteatoma is a potentially life-threatening inflammatory lesion that causes hearing loss, ear discharge, and ear pain, and serious complications. For the past several decades, most studies of cholesteatoma have been restricted to microscopic ear surgery. However, a growing body of evidence suggests endoscopic ear surgery is a safe, minimally invasive approach for cholesteatoma management. This thesis aim to investigate and compare the clinical effect between endoscopic and microscopic ear surgery of cholesteatoma. Materials and methods: The retrospective study included 186 patients with cholesteatoma who received endoscopic or microscopic ear surgery from 11 otorhinolaryngology centers between November 2016 and March 2021. Patients were followed-up for at least 1 year. Audiometry improvement, treatment cost, time, graft success rate and recurrence rate were assessed after surgery.

NCT ID: NCT04959539 Completed - Cholesteatoma Clinical Trials

Endoscopic Transcanal Tympanoplasty With Attico-antrostomy Versus Endoscopic-assisted Canal Wall up Mastoidectomy in Management of Localized Cholesteatoma: A Randomized Clinical Trial

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

the main objective of the study is to compare endoscopic transcanal tympanoplasty with attico-antrostomy with endoscopic assisted canal wall up mastoidectomy in treatment of limited attic cholesteatoma.

NCT ID: NCT04672187 Completed - Clinical trials for Middle Ear Cholesteatoma

Associations of Pre- and Intraoperative Endoscopic Findings of Middle Ear Status in Cholesteatoma

Start date: November 1, 2017
Phase:
Study type: Observational

The aim of this study is to assess the accuracy of preoperative HRCT of the temporal bone combined with the preoperative audiologic assessment compared with the intraoperative endoscopic middle ear finding.

NCT ID: NCT04551612 Not yet recruiting - Clinical trials for Cholesteatoma, Middle Ear

Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma

Start date: October 1, 2020
Phase:
Study type: Observational

Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations