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Clinical Trial Summary

Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations

Clinical Trial Description

Cholesteatoma has three Classical forms: (1) Congenital, primary or genuine cholesteatoma: occurs behind an intact tympanic membrane. Primary acquired cholesteatoma: looks like a limited diverticulum of the pars flaccida with little or no history of otorrhea. Secondary acquired cholesteatoma: develops with posterosuperior perforations in eardrum and expansion of the disease process into the antrum, mastoid, attic and middle ear. Granulation tissue, polyps and foul- smelling otorrhea are common findings in this type ;

Study Design

Related Conditions & MeSH terms

NCT number NCT04551612
Study type Observational
Source Assiut University
Status Not yet recruiting
Start date October 1, 2020
Completion date October 1, 2022

See also
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Recruiting NCT06246682 - Impact of Mastoid Condition on Results of Endoscopic Management of Cholesteatoma N/A
Completed NCT02554422 - Objective Measurement of Ossicular Chain Mobility Using a Palpating Instrument Intraoperatively N/A