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Cholesteatoma clinical trials

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NCT ID: NCT06016335 Completed - Hearing Loss Clinical Trials

MRI-based Synthetic CT Images of the Head and Neck

Start date: September 22, 2022
Phase: N/A
Study type: Interventional

In case of surgical procedures in the head and neck region, MRI in combination with CT of the bone is often the standard modality to visualise bony landmarks for planning, navigation and risk assessment. An important downside of a CT scan is the associated radiation exposure, especially in children. An additional downside is the sedation or general anaesthesia needed for both the MRI and CT scan session in very young children. These downsides could be removed if the CT scan can be substituted by an MRI sequence that can provide the same information as CT. This project aims to determine the feasibility of recreating CT like images of the craniofacial bones from MRI images using machine learning techniques.

NCT ID: NCT05182268 Completed - Clinical trials for Endoscopy; Microscopy; Ear Surgery; Cholesteatoma; Clinical Effect

Comparison of Clinical Effect Between Endoscopic and Microscopic Ear Surgery of Cholesteatoma: A Multicenter Retrospective Observational Study

Start date: November 1, 2016
Phase:
Study type: Observational

Background: Cholesteatoma is a potentially life-threatening inflammatory lesion that causes hearing loss, ear discharge, and ear pain, and serious complications. For the past several decades, most studies of cholesteatoma have been restricted to microscopic ear surgery. However, a growing body of evidence suggests endoscopic ear surgery is a safe, minimally invasive approach for cholesteatoma management. This thesis aim to investigate and compare the clinical effect between endoscopic and microscopic ear surgery of cholesteatoma. Materials and methods: The retrospective study included 186 patients with cholesteatoma who received endoscopic or microscopic ear surgery from 11 otorhinolaryngology centers between November 2016 and March 2021. Patients were followed-up for at least 1 year. Audiometry improvement, treatment cost, time, graft success rate and recurrence rate were assessed after surgery.

NCT ID: NCT04959539 Completed - Cholesteatoma Clinical Trials

Endoscopic Transcanal Tympanoplasty With Attico-antrostomy Versus Endoscopic-assisted Canal Wall up Mastoidectomy in Management of Localized Cholesteatoma: A Randomized Clinical Trial

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

the main objective of the study is to compare endoscopic transcanal tympanoplasty with attico-antrostomy with endoscopic assisted canal wall up mastoidectomy in treatment of limited attic cholesteatoma.

NCT ID: NCT04672187 Completed - Clinical trials for Middle Ear Cholesteatoma

Associations of Pre- and Intraoperative Endoscopic Findings of Middle Ear Status in Cholesteatoma

Start date: November 1, 2017
Phase:
Study type: Observational

The aim of this study is to assess the accuracy of preoperative HRCT of the temporal bone combined with the preoperative audiologic assessment compared with the intraoperative endoscopic middle ear finding.

NCT ID: NCT04489550 Completed - Clinical trials for Middle Ear Cholesteatoma

How Long Must the MRI Follow-up Last to Safely Identify Middle Ear Residual Cholesteatoma

Start date: January 1, 2013
Phase:
Study type: Observational

Previous studies demonstrated the high diagnostic value of non-echoplanar diffusion weighted magnetic resonance imaging (non-EP DWI) for residual cholesteatoma. However, limited data are available regarding a suitable length of imaging follow-up. The present study aimed to determine the optimal duration of non-EP DWI follow-up for residual cholesteatoma

NCT ID: NCT02554422 Completed - Clinical trials for Cholesteatoma, Middle Ear

Objective Measurement of Ossicular Chain Mobility Using a Palpating Instrument Intraoperatively

PalpEar
Start date: December 2013
Phase: N/A
Study type: Interventional

Feasibility of the objective measurement of the ossicular chain mobility, by using a force-measuring device based on a fiber optics sensors (PalpEar).

NCT ID: NCT02019888 Completed - Clinical trials for Hearing Loss, Sensorineural

Wide Frequency Band Test of Hearing in Veterans

CWTBAFV
Start date: December 1, 2014
Phase:
Study type: Observational

The accurate assessment of auditory status is critical for planning treatment for Veterans with hearing loss to include medical and audiological management. Current physiologic tests of auditory function in the standard clinical audiological test battery for Veterans have limited sensitivity in detecting some middle-ear disorders, and do not include a direct test of cochlear function. Recent studies have shown promise for new wide-bandwidth (WB) tests of absorbance for improved sensitivity in the assessment of middle-ear function including acoustic reflex testing. The addition of WB tests of cochlear function included in the WB test battery provides an opportunity to improve audiological diagnosis of a range of hearing disorders in Veterans. The automation provided by the WB test battery could provide additional benefits in reducing the duration of the evaluation, leaving more time for evaluation of test findings and counseling. Results from this study may lead to the improvement of audiological care for Veterans with hearing loss.

NCT ID: NCT01855425 Completed - Otosclerosis Clinical Trials

Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose

CBCT-ENT
Start date: September 21, 2012
Phase: N/A
Study type: Interventional

The study objective is to compare the CBCT images generated by the CS 9300 to those generated by conventional CT.

NCT ID: NCT01638052 Completed - Cochlear Implant Clinical Trials

Great Auricular Nerve Block for Children Undergoing Tympanomastoid Surgery

Start date: February 2006
Phase: Phase 2
Study type: Interventional

The investigators goal is to determine the efficacy and duration of analgesia with the addition of Clonidine, an alpha-2 agonist, to local anesthetic blockade using bupivacaine, of the great auricular nerve in children undergoing tympanomastoid surgery.

NCT ID: NCT00682409 Completed - Cholesteatoma Clinical Trials

Magnetic Resonance (MR) Imaging in the Post Operative Follow-up of Cholesteatoma in Children

Start date: January 2008
Phase: N/A
Study type: Interventional

Classical imaging techniques are inaccurate to detect residual cholesteatoma. The aim of our study is to evaluate the value of diffusion-weighted MR imaging and delayed contrast enhanced T1 weighted spin-echo sequences in the detection of residual cholesteatoma in children, in a large serie of surgically verified cases.