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NCT01812785 Clinical Trial

Study to Investigate the Causes of Fever in Children Living in Urban Dar es Salaam and Rural Ifakara

Children Clinical Trial

Official title:
Study to Investigate the Causes of Fever in Children Living in Urban Dar es Salaam and Rural Ifakara

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01812785
Other study ID # Feverstudy
Secondary ID SNSF
Status Completed
Phase N/A
First received March 14, 2013
Last updated March 14, 2013
Start date January 2008
Est. completion date December 2011

Study information
Verified date March 2013
Source Swiss Tropical & Public Health Institute
Contact n/a
Is FDA regulated No
Health authority Tanzania: National Institute for Medical ResearchSwitzerland: Ethikkommission
Study type Observational

Clinical Trial Summary

The goal is to improve the evidence-based management of fever cases seen in outpatient clinics in malaria endemic countries, through a better understanding of the value of accurate malaria diagnosis, and through an improved understanding of the other causes of fever in children. The objective is to describe systematically (as much as possible) the etiologies of fever in children in an urban and in a rural environment of sub-Saharan Africa.

Recruitment information / eligibility
Status Completed
Enrollment 1010
Est. completion date December 2011
Est. primary completion date December 2008
Accepts healthy volunteers No
Gender Both
Age group 2 Months to 10 Years
Eligibility Inclusion Criteria:

- axillary temperature of 38°C or more

- first consultation for the present problem

- history of fever lasting for one week or less

- main complaint was not an injury or trauma

- no report of an antimalarial or antibiotic medicine taken during the previous week

Exclusion Criteria:

- severe malnutrition

- categorized as P1 (requiring immediate live saving procedures)

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Tanzania Amana district hospital Dar es Salaam
Tanzania St Francis hospital Ifakara Morogoro

Sponsors (2)
Lead Sponsor Collaborator
Swiss Tropical & Public Health Institute University Hospital, Geneva

Country where clinical trial is conducted

Tanzania, 

Outcome
Type Measure Description Time frame Safety issue
Primary Proportion of each disease and proportion of fevers of unknown origin in febrile children aged 2 months to 10 years attending an Outpatient Department of a district hospital in Dar es Salaam and in Ifakara December 2011 No
Secondary Clinical and laboratory predictors of each disease December 2011 No
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