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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03696602
Other study ID # enf4327
Secondary ID
Status Completed
Phase
First received
Last updated
Start date July 1, 2006
Est. completion date September 30, 2016

Study information

Verified date September 2018
Source Central Hospital, Nancy, France
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Deep inhalation (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation. The hypothesis tested was that DI induces more relaxation in methacholine induced bronchoconstriction—solely determined by the smooth muscle contraction—than in exercise induced bronchoconstriction, which is contributed to by both smooth muscle contraction and airway wall inflammation.


Description:

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Study Design


Related Conditions & MeSH terms


Intervention

Diagnostic Test:
bronchial provocation test


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Central Hospital, Nancy, France

Outcome

Type Measure Description Time frame Safety issue
Primary Grs change between before deep breath and after deep breath in exercise and metacholine groups GrsDI represents Grs measured after deep breath reported to Grs before deep breath (bronchial provocation test) through study completion, an average of 1 hour
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