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Child clinical trials

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NCT ID: NCT02852928 Recruiting - Child Clinical Trials

European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and Biobank

chILD-EU
Start date: December 2013
Phase:
Study type: Observational [Patient Registry]

Generation of a common European database and biobank Continous assessment and implementation of guidelines and treatment protocols Establishment of a large observational cohort of chILD patients Determination the value of outcomes used in child Assess treatment variations used, deliver data from defined protocols and linked outcomes

NCT ID: NCT02846714 Completed - Melanoma Clinical Trials

Family Lifestyle Actions and Risk Education Study

FLARE
Start date: July 2016
Phase: N/A
Study type: Interventional

The overall purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of a family-focused behavioral intervention ("FLARE", which stands for Family Lifestyle Actions and Risk Education) that aims to improve adherence to melanoma preventive behaviors among children at elevated risk for the disease.

NCT ID: NCT02830698 Terminated - Abdominal Pain Clinical Trials

Abdominal Pain Disorders Functional in Children: Impact of Hypno-analgesia on the Autonomic Balance

Start date: May 31, 2017
Phase:
Study type: Observational

Abdominal pain disorders functional (including functional dyspepsia, irritable bowel syndrome, abdominal migraine, functional abdominal pain) is a very common disease in the pediatric population, where classical medical treatment does not always prove effective. This clinical entity has an impact on the individual physiological balance particularly on the autonomic regulation. Studies concerning adults with irritable bowel syndrome, showed significant changes in heart rate variability indices (HRV: heart rate variability). The study of time and frequency domain analysis of HRV allows noninvasive and reproducible assessment of the cardiac sympathetic and parasympathetic tone. The investigators hypothesize that the sympathovagal balance could be altered in children in case of prolonged nociceptive stress as the investigators find it especially in irritable bowel syndrome and functional abdominal pain. In recent years, the control of pediatric pain experienced considerable growth through hypnosis techniques and several studies have shown analgesic efficacy with a beneficial effect in terms of quality of life in children. Our study aims to assess the impact of the hypno-analgesia treatment of Abdominal pain disorders functional on sympathovagal balance. The investigators propose to realize in 7 to 18 years old children with Abdominal pain disorders functional a single center prospective study to highlight after a standardized hypnosis program, changes in the time and frequency domain indices of heart rate variability and clinical or quality of life parameters. The primary endpoint will be the high frequency HF indice. Secondary endpoints will be the other indices of HRV (Ptot, VLF, LF, ratio LF / HF, SDNN, SDANN, pNN50, RMSSD), the Quality of Life Questionnaire values (PedsQL ™ 4.0) a pain scale and the composite score of Francis.

NCT ID: NCT02794103 Completed - Pain Clinical Trials

Virtual Reality Distraction for Procedural Pain Management and Anxiety in Children With Burn Injuries : A Pilot Study

Start date: June 2016
Phase: N/A
Study type: Interventional

Procedural pain is the most intense and often undertreated pain associated with burn injuries. The use of analgesics does not always provide optimal relief and is accompanied by several side effects. Indeed, children with burn injuries still experience severe pain intensity during procedures despite the fact that doses of analgesics used with this population has almost doubled in the last twenty years. Current guidelines on pediatric procedural pain management recommend the combination of non-pharmacological and pharmacological interventions to enhance pain management and decrease the numerous side effects of analgesics. Distraction has been identified among the most effective non-pharmacological interventions for pain as it diverts the child's attention to an attractive element, hindering the perception of the painful stimuli. Virtual reality (VR) is a method of active distraction that offers the child a multi-sensory immersive interaction that found many applications for pain management in adult patients. However, very few studies have tested the efficacy of distraction by virtual reality on procedural pain and anxiety in children with burn injuries. The aim of this study is to assess the feasibility and preliminary efficacy of a virtual reality prototype developed specifically for the hydrotherapy room of children under seven years old for the relief of procedural pain and anxiety in children with burn injuries. HYPOTHESES: a) VR distraction is a feasible non-pharmacological intervention for pain management during hydrotherapy, b) VR distraction combined with analgesics is more efficacious than standard treatment (analgesics alone) on procedural pain and anxiety (hydrotherapy) of young children with burn injuries.

NCT ID: NCT02762786 Completed - Child Clinical Trials

Effectiveness of Musical Training in Children From Low Income Families

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

This study aims to examine the effectiveness of musical training in promoting happiness and quality of life of preschool children from low-income families. Participants in the experimental group will attend a weekly 1-hour musical training lesson for 12 weeks conducted by the Music Children Foundation. While participants in the waitlist control group received the same training after the experimental group had completed the intervention.

NCT ID: NCT02754973 Completed - Neoplasms Clinical Trials

Integrated Experiential Training Program With Coaching by Nursing Students in Childhood Cancer Patients

Start date: May 2015
Phase: N/A
Study type: Interventional

Background: Despite the evidence that regular physical activity can have beneficial effects on the physical and psychological well-being of cancer patients, a review of the literature reveals that a majority of young cancer patients fail to attain the same levels of physical activity that they had before contracting the disease. There is scientific evidence that physical inactivity induces muscle catabolism and atrophy and cardiovascular diseases, which may lead to a further increase in fatigue and a decrease in the functional capacity of cancer patients. Empirical evidence is needed to explore an appropriate strategy for promoting physical activity in such patients. Purposes: To examine the effectiveness of an integrated experiential training program with coaching by nursing students in promoting regular physical activity, reducing fatigue and enhancing quality of life among Hong Kong Chinese childhood cancer patients. Design and Subjects: A randomised controlled trial (RCT), two-group pre-test and repeated post-test, within and between subjects design will be conducted. Recruitment of subjects will be carried out in a paediatric oncology ward of a Hong Kong acute care hospital. Intervention: Participants in the experimental group will join an integrated experiential training program with coaching by nursing students, which contains 28 home visits by a designated nursing student as a coach for a 6-month period. Those in the placebo control group will receive an amount of time and attention (home visits by research assistants) that mimics that received by the experimental group.

NCT ID: NCT02754908 Completed - Child Clinical Trials

Effectiveness of Musical Training in Children Surviving Brain Tumours

Start date: January 2016
Phase: N/A
Study type: Interventional

This study aims to examine the effects of musical training on improving the neurocognitive function and psychological well-being of children surviving brain tumours. Half of the participants will receive weekly 45-minute lessons on musical training for one year (52 weeks) while the other half are the placebo controls.

NCT ID: NCT02738814 Enrolling by invitation - Child Clinical Trials

Propofol for Treatment on Emergence Agitation

Start date: April 2016
Phase: Phase 4
Study type: Interventional

This study aimed to verify the effects of propofol for treatment on emergence agitation (EA) after sevoflurane anesthesia in pediatric strabismus surgery.

NCT ID: NCT02725645 Completed - Child Clinical Trials

Backpack Load and Spine Muscles Activity

BLSMA
Start date: June 2014
Phase: N/A
Study type: Interventional

The purpose of the present study is to analyze the influence of four backpack loading conditions (0, 10, 15 and 20% of body weight) on the electromyographic activity of the neck and lumbar muscles of elementary school children.

NCT ID: NCT02720380 Completed - Asthma Clinical Trials

Buteyko Method for Children With Asthma

Start date: July 2015
Phase: N/A
Study type: Interventional

This study has the aim to assess the effectiveness of the Buteyko method as an adjunct therapy in the treatment of children with asthma.