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Child, Only clinical trials

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NCT ID: NCT06463067 Completed - Child, Only Clinical Trials

Books, Videos And Mobile Games İn Pediatric Dentistry

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The objective of this study was to examine the impact of educational video viewing, reading educational books, and playing educational mobile games on children's dental anxiety prior to dental examinations. The main questions it aims to answer are: 1. Does reading educational books before dental examinations reduce dental anxiety in children? 2. Does watching educational videos before dental examinations reduce children's dental anxiety? 3. Does playing educational mobile games before dental check-ups reduce dental anxiety in children?

NCT ID: NCT06455592 Not yet recruiting - Sleep Clinical Trials

Effect of APA on Sleep Quality in Children With Cancer From 5 to 16 Years

APANYX
Start date: September 2024
Phase: N/A
Study type: Interventional

Main objective : Evaluate the effect of adapted physical activity on the sleep of children with cancer from 5 to 16 Hypothesis : Practice daily adapted physical activity improve the sleep of the 5 to 16 children with cancer

NCT ID: NCT06444282 Not yet recruiting - Emergencies Clinical Trials

Emergency Care Action Plans for Infants With Medical Complexity

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

An Emergency Care Action Plan (ECAP) is a tool intended to be helpful to providers when treating a child with complex medical needs during an emergency. Once created, ECAPs are added to the Electronic Health Record (EHR), shared with the child's caregiver(s), and kept up by all of those involved in a child's care. The goal of this study is to measure important health outcomes (ex. inpatient days, emergency department visits) in terms of the use of the ECAP for infants discharged from the Neonatal Intensive Care Unit (NICU). This study will also measure other real-time potential challenges related to the use of the ECAP including, but not limited to, if it is being used, if providers and caregivers want to use it, and if they keep using it over a long period of time.

NCT ID: NCT06436651 Recruiting - Cancer Clinical Trials

Digital Storytelling in Symptom Management Pediatric Oncology

Start date: November 13, 2023
Phase: N/A
Study type: Interventional

The aim of this clinical study is to evaluate the effectiveness of the digital storytelling method in symptom management in children diagnosed with oncology. It will also provide information about children's experiences with Digital Storytelling and the use of the method. The main questions it aims to answer are: - Is there a difference between the anxiety scores of children who applied the Digital Storytelling Method and those who did not? - Is there a difference between the fatigue scores of children who applied the Digital Storytelling Method and those who did not? - Is there a difference between the nausea scores of children who applied the Digital Storytelling Method and those who did not? - Is there a difference between the pain scores of children who applied and did not apply the Digital Storytelling Method? Participants: Complete the first stage data forms. Visit the clinic every 7-15 days for the digital storytelling process, which consists of 4 stages. After the storytelling process is completed, have a process evaluation meeting with the researcher.

NCT ID: NCT06426147 Not yet recruiting - Infections Clinical Trials

L-citrulline to Improve Adverse Outcomes in Admitted Children (EChiLiBRiST, Clinical Trial 2, Inpatients)

Start date: January 1, 2025
Phase: N/A
Study type: Interventional

In low and middle-income countries, children admitted to hospital are not similarly ill, and do not all have a comparable prognosis. In fact, understanding at first encounter their risk of developing adverse outcomes (including mortality) could allow a more focused management and the tailoring of specific interventions to decrease in hospital mortality, and post discharge adverse longer-term outcomes. This clinical trial, part of the EChiLiBRiST larger project ("Development and validation of a quantitative point-of-care test for the measurement of severity biomarkers to improve risk stratification of fever syndromes and enhance child survival") has the two-fold objective of: 1. Assessing whether a POINT-OF-CARE rapid triaging test (PoC RTT) based on the quantitative measurement at the bedside of the "prognostic" biomarker sTREM-1 (soluble-triggering receptor expressed on myeloid cells 1) can reliably identify those admitted children with a higher risk of adverse outcomes; and 2. Assessing whether the therapeutic intervention (the L-arginine precursor, L-Citrulline, key in the nitric oxide biosynthesis), administered orally for 28 days to those children aged 1-<60 months identified as "moderate-to-high risk" by the prognostic biomarker can improve outcomes as compared to those receiving an indistinguishable placebo. This second objective will be assessed in a prospective multi-country, multi-site, individually randomised, two-arm, placebo-controlled, double blind clinical trial involving ~888 children 1-<60m of age admitted to hospital and determined to be at high risk of adverse outcomes by their baseline sTREM-1 levels. The trial will compare the efficacy of a twice-daily dose of L-citrulline syrup vs placebo (200-300mg/kg/day depending on weight-band; for 28 days) in reducing adverse outcomes in children with severe disease. The trial will be running independently but in parallel in two high-mortality settings in Mozambique and in Ethiopia.

NCT ID: NCT06423131 Recruiting - Clinical trials for Hematopoietic Stem Cell Transplantation

Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Start date: May 26, 2024
Phase: N/A
Study type: Interventional

This is a single-center prospective, non-randomized controlled clinical study in China using CliniMACS TCRα/β+ cell depleted stem cell haploidentical donors versus conventional Beijing protocol for haploidentical hematopoietic stem cell transplantation in children.

NCT ID: NCT06422338 Not yet recruiting - Child, Only Clinical Trials

A Rapid Triage Test to Improve Risk-stratification of Febrile Children (EChiLiBRiST, Clinical Trial 1, Outpatients)

Start date: December 1, 2024
Phase: N/A
Study type: Interventional

The overall aim of the study is to provide evidence that introducing soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) evaluation at triaging (first clinical assessment), in combination with IMCI-based guidelines (SoC), is a viable strategy to enhance rapid and accurate identification of febrile children at increased risk of life-threatening infections compared to IMCI-based strategies alone (SoC), and to demonstrate whether this results in enhanced decisions of admission/referral vs discharge, and enhanced overall health outcome of children with acute fever in sub-Saharan Africa.

NCT ID: NCT06421779 Recruiting - Pain Clinical Trials

The Effect of Virtual Reality (VR) on Skin Prick Test Related Pain and Fear in Children

Start date: March 22, 2024
Phase: N/A
Study type: Interventional

This study aims to show the effect of VR on skin prick test-related pain and fear in children. The investigators will compare the effect of VR on skin prick test-induced pain and fear in children applying to the Pediatric Allergy outpatient clinic with controls who underwent skin prick test without the use of VR.

NCT ID: NCT06364280 Not yet recruiting - Critical Illness Clinical Trials

Pediatric Prehospital Airway Resuscitation Trial

Pedi-PART
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

This study is a Phase 3, multi-center, Bayesian Adaptive Sequential Platform Trial testing the effectiveness of different prehospital airway management strategies in the care of critically ill children. Emergency Medical Services (EMS) agencies affiliated with the Pediatric Emergency Care Applied Research Network (PECARN) will participate in the trial. The study interventions are strategies of prehospital airway management: [BVM-only], [BVM followed by SGA] and [BVM followed by ETI]. The primary outcome is 30-day ICU-free survival. The trial will be organized and executed in two successive stages. In Stage I of the trial, EMS personnel will alternate between two strategies: [BVM-only] or [BVM followed by SGA]. The [winner of Stage I] will advance to Stage II based upon results of Bayesian interim analyses. In Stage II of the trial, EMS personnel will alternate between [BVM followed by ETI] vs. [Winner of Stage I].

NCT ID: NCT06361069 Completed - Anxiety Clinical Trials

Reducing Anxiety in Children Undergoing Day Surgery

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Aim: This study was conducted to determine the efficacy of finger puppets, distraction cards and kaleidoscope for reducing anxiety in children undergoing day surgery. Methods: The study was conducted using the "pre-post test unmatched group model", one of the quasi-experimental methods. The study was conducted between April 2023 and January 2024 with children aged 6-12 years who were admitted to the pediatric clinic of a hospital for day surgery. A total of 85 children (including 20 children in the control group, 22 children in the finger puppet intervention group, 21 children in the distraction cards intervention group, and 22 children in the kaleidoscope intervention group) who were hospitalized in the pediatric clinic between April 2023 and January 2024 and who met the inclusion criteria were included in the study. Descriptive statistics, Mann Whitney U test, Kruskal Wallis and regression analysis were used in the evaluation of the data.