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Cesarean Section clinical trials

View clinical trials related to Cesarean Section.

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NCT ID: NCT05900492 Active, not recruiting - Cesarean Section Clinical Trials

Incidence of Uterine Cesarean Scar Niche After Cesarean Delivery

Start date: January 1, 2023
Phase:
Study type: Observational

To assess the incidence of cesarean scar niche and its risk factors in a prospectively collected population.

NCT ID: NCT04965779 Active, not recruiting - Cesarean Section Clinical Trials

The Effect of Abdominal Binder Use on Postpartum Pain, Bleeding, and Breastfeeding Success in Cesarean Delivery Women

Start date: September 22, 2020
Phase: N/A
Study type: Interventional

The aim of this randomized controlled interventional study is to identify the effect of the use of an abdominal binder on postpartum pain, bleeding, and breastfeeding success in primiparous women who have undergone planned cesarean delivery with spinal anesthesia.

NCT ID: NCT04038307 Active, not recruiting - Cesarean Section Clinical Trials

Pre-emptive Paracetamol for Prevention of Intraoperative Shoulder Tip Pain

Start date: August 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

the aim is to determine the efficacy of Paracetamol in reducing the incidence and severity of intraoperative shoulder pain in patients undergoing cesarean section.

NCT ID: NCT03760718 Active, not recruiting - Cesarean Section Clinical Trials

Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery

CLOR-PRO
Start date: September 30, 2019
Phase: Early Phase 1
Study type: Interventional

The long term objective is to show that intraperitoneal chloroprocaine can be used an alternative option to avoid general anesthesia during cesarean delivery, to alleviate mother's discomfort from surgical pain, reduce complications, and improve the birth experience. The objectives in this study are to determine the amount of chloroprocaine that is absorbed into the blood in order to create a plasma concentration time profile and to determine the incidence of side effects to help guide selection of an appropriate concentration for future study.

NCT ID: NCT03645239 Active, not recruiting - Pain, Postoperative Clinical Trials

Post-operative Emesis and Pain Outcomes After Cesarean Delivery

EPOC
Start date: May 24, 2018
Phase:
Study type: Observational

Approximately 20% women who undergo cesarean delivery would suffer from severe post-operative pain, which may further increase their risks from developing postpartum depression. Predictive factors such as pre-operative pain, age and anxiety could significantly contribute to post-operative nausea and vomiting (PONV) and pain in general surgery, however little information is available with regards to cesarean delivery. The investigators would investigate the risk factors of causing post-operative emesis after cesarean delivery, and to reaffirm that there is a positive correlation between pain on local anesthetic injection, presence of mechanical temporal summation (MTS) and post-Cesarean pain scores.

NCT ID: NCT03195309 Active, not recruiting - Cesarean Section Clinical Trials

A Comparison of Different Concentration Ropivacaine for Patient-controlled Epidural Analgesia

PCEA
Start date: January 20, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

To compare the postoperative analgesic effect and the intensity of motor block in different concentration ropivacaine plus fentanyl when used epidurally with a patient-controlled analgesia device after Cesarean delivery.

NCT ID: NCT02836626 Active, not recruiting - Cesarean Section Clinical Trials

Fascial Scar Mobilization Techniques in Treating Chronic Caesarian Section Scar Pain

Start date: June 2016
Phase: N/A
Study type: Interventional

Over 1.37 million Caesarian sections (C-sections) are performed annually in the US . It is estimated that 12-20 % of those will result in chronic scar pain. This pain can lead to functional difficulties performing activities of daily living, pain with bowel movements, and pain with sexual activity . There is anecdotal evidence supporting the use of deep fascial scar mobilization techniques in reducing abdominal surgical scar pain, and yet almost no research has been published. The aims of this randomized clinical trial will be to determine if deep fascial scar mobilization techniques or superficial scar mobilization techniques will improve chronic pain and its resulting functional deficits, threshold pressure discomfort, pressure tolerance and mobility restrictions resulting from C-section surgery and to see if these interventions are more effective than no intervention. A positive result may result in an increase in the use of this intervention and thus the reduction of chronic scar pain for many women; it may provide justification for insurance reimbursement for this approach and it will also pave the way for further investigation into the use of these techniques with other types of painful scars including hysterectomy.

NCT ID: NCT02609217 Active, not recruiting - Cesarean Section Clinical Trials

Parents' Expectations and Experiences Around Cesarean Section in Belgium

Start date: November 2015
Phase: N/A
Study type: Observational

The aim of this study is to gain insight in the experiences and expectations of Belgian parents concerning primary cesarean section. This will be achieved by structured patient interviews and questionnaires in 24 women undergoing the procedure and their partners. This group will be divided into two subgroups of 12 multiparous and 12 nulliparous women and their partners.

NCT ID: NCT02029898 Active, not recruiting - Anesthesia Clinical Trials

Remifentanil for General Anesthesia in the Context of Immaturity

REAGI
Start date: February 2014
Phase: Phase 1/Phase 2
Study type: Interventional

One of the problems during general anesthesia (GA) for caesarean section is the place of opioid agents. Indeed, the literature does not provide so far a clear answer regarding the use of opioids prior to extraction of the newborn. Indeed, if the opioid administration at induction is beneficial for the mother (better control of autonomic responses to noxious stimuli), the impact on the newborn can be unfavorable in terms of adaptation to extrauterine life . This is especially true if the birth takes place in a context of prematurity and / or acute fetal distress. The pharmacokinetics of remifentanil make it the only opioid which is consistent with a rapid sequence induction. Its short period of action avoids the manual ventilation of patients before intubation, while providing a peak of action concomitant to the nociceptive stimulation. Patients at high risk of aspiration, including pregnant women, may benefit from this type of morphine at induction. In addition, the fact that remifentanil seems to be associated with relative fetal safety in obstetrical or neonatal context legitimized the development of protocols to study maternal-fetal consequences of the use of remifentanil at induction of AG for emergency caesarean section. While cesarean section under general anesthesia mainly concern premature newborns in France, no work has focused on the use of remifentanil for caesarean section in a context of preterm without preeclampsia. The main hypothesis of this study is to evaluate the safety of the use of remifentanil in terms of adaptation to extrauterine life in children born prematurely by caesarean section under general anesthesia outside the context of preeclampsia. To do this, we will compare two groups of children, one consisting of children born by cesarean section under general anesthesia with maternal remifentanil infusion, the other made up of children born by cesarean section under general anesthesia without maternal infusion of remifentanil. This study is prospective, single-center, randomized, double-blinded. The primary endpoint is formed by the value of the Apgar score less than 7 at 5 minutes, calculated in the delivery room by the team supporting the child (midwives and pediatricians). The secondary endpoints are formed by maternal hemodynamic parameters (SBP, DBP, MAP, HR), the rate of complications during induction (difficult intubation, aspiration), the onset of respiratory distress requiring ventilation mask in the newborn, the rate of intubation in neonates, and the rate of use of adjuvant anesthetic agents.

NCT ID: NCT00293683 Active, not recruiting - Cesarean Section Clinical Trials

A Study Comparing Two Different Techniques for Closing the Skin After a Cesarean Delivery

Start date: December 2004
Phase: N/A
Study type: Interventional

We hypothesize that the use of absorbable staples to close cesarean skin incisions will cause less pain, have better long-term cosmetic results, and result in improved patient satisfaction over standard metal staples. We expect to see no difference in wound complication rates with these two cesarean skin closure techniques.