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Cervical Spondylosis clinical trials

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NCT ID: NCT03320759 Recruiting - Clinical trials for Spinal Cord Injuries

Enhancing Recovery in Non-Traumatic Spinal Cord Injury

Start date: August 21, 2018
Phase: N/A
Study type: Interventional

The investigators have spent the last decade uncovering unique metabolic and functional abnormalities in the brains of patients with spinal cord compression. Degenerative spinal cord compression represents a unique model of reversible spinal cord injury. In the investigator's previous work, they have demonstrated that cortical reorganization and recruitment is associated with metabolic changes in the brains of patients recovering from spinal cord compression and is correlated with recovery and improved neurological scores. The goal of this study is to combine a rigorous platform of clinical care that includes preoperative evaluation, surgery, and rehabilitation, with state of the art imaging techniques to demonstrate how rehabilitative therapy can increase brain plasticity and recovery of neurological function in patients with spinal cord injury. Neurological function will be carefully evaluated in two groups of patients, those receiving rehabilitation and those not receiving rehabilitation after spine surgery, and will be correlated with the results of advanced imaging.

NCT ID: NCT02819089 Recruiting - Clinical trials for Cervical Spondylosis

Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant

Start date: May 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the recovery profiles after general anesthesia in patient undergoing anterior cervical spine surgery. This study will compare the Riker sedation agitation scores between two groups, with or without dexmedetomidine as an anesthetic adjuvant.

NCT ID: NCT02814825 Completed - Clinical trials for Cervical Spondylosis

An ACDF Multi-Center Study Using ViviGen Cellular Bone Matrix

Start date: June 1, 2016
Phase:
Study type: Observational

The purpose of this post-market study is to collect data on ViviGen and how its use affects fusion rates in the cervical spine when used as additional grafting material to fill the cervical spacer. The patient population of interest is patients who have already elected to undergo a 2-3 level ACDF surgical procedure using ViviGen, per standard of care.

NCT ID: NCT02758899 Terminated - Diabetes Clinical Trials

Diabetes and Glycosylation in Cervical Spondylosis

Start date: March 2014
Phase:
Study type: Observational

The purpose of this study is to determine the relevant significance of diabetes on cervical disc degeneration, and correlate diabetic control (HgbA1C) with disc glycosylation profile in patients undergoing anterior cervical discectomy and fusion for cervical spondylosis. Additionally, to compare the level of degenerative cervical disc glycosylation in patients with and without diabetes. Hypothesis: Patients with diabetes and degenerative cervical disc disease have higher levels of disc tissue glycosylation, and higher levels of glycosylation are correlated with poor outcomes.

NCT ID: NCT02276911 Terminated - Clinical trials for Cervical Spondylosis

Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery

Start date: March 1, 2015
Phase: Phase 2
Study type: Interventional

A prospective, randomized, placebo controlled, double-blinded study at a single institution.

NCT ID: NCT01616719 Withdrawn - Clinical trials for Cervical Radiculopathy

Evaluation of DTRAX Graft in Patients With Cervical Degenerative Disc Disease

Start date: May 2012
Phase: N/A
Study type: Interventional

DTRAX Graft is used to relieve nerve pressure in the neck in order to provide relief for Cervical Degenerative Disc Disease. This study is being conducted to determine the effectiveness of the graft, and to find out whether or not it provides better results or faster healing than traditional ways of performing surgery for Cervical Degenerative Disc Disease.

NCT ID: NCT01243684 Completed - Clinical trials for Cervical Spondylosis

A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis

Tractocervical
Start date: September 2010
Phase: N/A
Study type: Interventional

This study aims at evaluating spinal cord structure using diffusion tensor imaging in patients with cervical spondylosis.

NCT ID: NCT01061697 Completed - Clinical trials for Cervical Spondylosis

Pregabalin and Radicular Pain Study (PARPS)

PARPS
Start date: January 2008
Phase: Phase 4
Study type: Interventional

This study is designed to investigate the effectiveness of pregabalin (Lyrica) on nerve pain caused by degenerative neck problems. Pregabalin is a new drug registered for use in nerve pain worldwide

NCT ID: NCT00788008 Completed - Knee Osteoarthritis Clinical Trials

Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly

Start date: November 2008
Phase: N/A
Study type: Interventional

The purpose of this research is to determine if post-operative cognition will be better if the general anesthesia for surgery is done with an inhaled (gas through a breathing tube) or intravenous (medicine injected in the IV) general anesthetic technique.