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Cervical Spine Degeneration clinical trials

View clinical trials related to Cervical Spine Degeneration.

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NCT ID: NCT06428981 Completed - Clinical trials for Cervical Spine Degeneration

Surgical Intervention on the Body-mind-spirit of Patients With Cervical Spine Surgery

Start date: August 2, 2022
Phase: N/A
Study type: Interventional

The study aimed to evaluate if surgical intervention in patients with degenerative cervical diseases improves quality of life (QOL), lowers pain-induced mental impairment, improves psychologic health, and promotes spiritual well-being.

NCT ID: NCT06202443 Recruiting - Clinical trials for Cervical Spine Degeneration

Improving Surgical Outcomes With Early PT After ACDF

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The goal of this two-group randomized clinical trial is to examine the effects of early postoperative PT compared to delayed postoperative PT for improving outcomes after hospital discharge for ACDF surgery. The main question this clinical trial aims to answer are: - Whether early PT participants will demonstrate greater improvements in outcomes compared to delayed PT participants. - Whether improvements in cervical strength and handgrip strength, cervical endurance, and cervical range of motion will be associated with improvements in outcomes. Participants will be randomized to one of two groups (early PT or delayed PT) and outcomes compared across groups.

NCT ID: NCT05408923 Withdrawn - Clinical trials for Lumbar Spine Degeneration

Randomized Controlled Trial Comparing Irrisept Versus Normal Saline for Wound Irrigation After Posterior Spine Surgery

Irrisept
Start date: July 2022
Phase: Phase 4
Study type: Interventional

To compare post-operative wound complications in patients randomized to normal saline versus Irrisept solution and any other adverse reactions from the solution.

NCT ID: NCT04222777 Completed - Aging Clinical Trials

Cervical Spine Motion in the Elderly

Start date: October 10, 2019
Phase: N/A
Study type: Interventional

Rationale: Physiological motion of the cervical spine is a subject of interest for medical specialists. Segmental range of motion (sROM) has been most commonly used to define motion but inter- and intra-variability is large. Therefore, a sequence of segmental contributions in the lower cervical spine during the second half of extension has been defined in healthy participants (uniform in 80-90%). The mean age of these participants was 23 years. Since cervical degenerative disc disease (CDDD) occurs more often in elderly patients, it is of paramount importance to study whether this sequence remains present during aging, regardless of losing 0.11 degrees of sROM each year. Objective: To investigate if the normal sequence of segmental contributions in the lower cervical spine during the second half of extension (C4-C5 followed by C5-C6, and then C6- C7) is also present in asymptomatic participants between 55 and 70 years of age by using cinematographic recordings. Study design: Fundamental research Study population: Eleven asymptomatic participants between 55 and 70 years of age, without a medical history of neck problems, with a score of 4 or less on the Neck Disability Index (NDI), and without severe degenerative changes based on a score of 3 or less on the radiological Kellgrens' classification. Intervention: Two flexion and extension cinematographic recordings of the cervical spine with a two-week interval between recordings. Main study parameters/endpoints: Primary endpoint: Defining the cervical spines' physiological motion pattern by analysing the normal sequence of segmental contributions in the lower cervical spine (C4-C5 followed by C5-C6, and then C6-C7) during the second halfof extension in asymptomatic participants between 55 and 70 years of age. Secondary endpoint: Determine sROM of C4-C5, C5-C6, and C6-C7 by analysing the flexion and extension cinematographic recordings in asymptomatic participants between 55 and 70 years of age. Nature and extent of the burden and risks associated with participation, benefit and group relatedness: Participants receive cinematographic recordings twice. There will be no follow-up.

NCT ID: NCT03955705 Enrolling by invitation - Clinical trials for Cervical Spine Degeneration

Analgesic Effectiveness of Nefopam in Patients Undergoing Anterior Cervical Spine Surgery

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

Nefopam is a benzoxazocine derivative which is non-opioid and non NSAIDs. The previous studies showed that nefopam can inhibit reuptake of serotonin, norepinephrine and dopamine. It has no respiratory depression so may be useful in potential airway compromized surgery like anterior cervical discectomy and fusion (ACDF). This study aims to study the analgesic properties of nefopam after ACDF.

NCT ID: NCT03312192 Withdrawn - Clinical trials for Degenerative Disc Disease

Stand-Alone Cage Verus Anterior Plating for Anterior Cervical Discectomy and Fusion.

Start date: July 17, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the clinical results between two different techniques for ACDF: 1. Stand-alone ACDF, which means the placement of an interbody device (cage) without anterior fixation or plating; 2. ACDF with and interbody cage and anterior plating for fixation. Both of these procedures are commonly performed at Rush with unclear advantage of one procedure over the other. Both have been associated with good to excellent clinical outcomes. The devices used in this study are approved by the Food and Drug Administration (FDA).