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Cerebral Palsy clinical trials

View clinical trials related to Cerebral Palsy.

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NCT ID: NCT04020354 Active, not recruiting - Cerebral Palsy Clinical Trials

Changes Induced by Early HABIT-ILE in Pre-school Children With Uni- and Bilateral Cerebral Palsy

EarlyHABIT-ILE
Start date: November 27, 2018
Phase: N/A
Study type: Interventional

Studying in two randomized controlled trials (RCT) the changes induced by early HABIT-ILE in functional, neuroplastic and biomechanical assessment in children with unilateral and bilateral CP.

NCT ID: NCT04017871 Completed - Cerebral Palsy Clinical Trials

Evaluation of Functional, Neuroplastic and Biomechanical Changes Induced by an Intensive, Playful Early-morning Treatment Including Lower Limbs (EARLY-HABIT-ILE) in Preschool Children With Uni and Bilateral Cerebral Palsy

HABIT-ILE
Start date: August 18, 2019
Phase: N/A
Study type: Interventional

An urgent priority in the field of paediatric neurorehabilitation is the development of effective early motor interventions. Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (= HABIT-ILE) applies the concepts of motor skill learning and intensive training to both the Upper Extremities (UE) and Lower Extremities (LE) and has been shown to improve aspects of motor function of the UE and LE in school age children with unilateral and bilateral Cerebral Palsy (CP) across the 3 levels of the International Classification of Functioning, Disability and Health (ICFDH). The principles and content of HABIT-ILE can be applied to pre-school children and this method is highly promising for early rehabilitation.

NCT ID: NCT04012125 Completed - Cerebral Palsy Clinical Trials

The Effect of Flexible Thoracolumbar Brace on Scoliosis in Cerebral Palsy

Start date: September 3, 2018
Phase: N/A
Study type: Interventional

The Effect of Flexible Thoracolumbar Brace on Scoliosis in Cerebral Palsy, Prospective, Randomized, Open-label Trial

NCT ID: NCT04009031 Terminated - Child Clinical Trials

Video Game for Home-based Rehabilitation for Children With Hemiplegia

Start date: October 9, 2018
Phase: N/A
Study type: Interventional

This study evaluates the feasibility of a low-cost, movement tracking video game (Bootle Blast) to 1) sustain engagement in children with cerebral palsy (CP) during a 12-week intervention; and 2) generate changes in upper limb functional motor outcomes following the intervention.

NCT ID: NCT03997591 Completed - Dementia Clinical Trials

Upper Limb Reeducation Across Life Span

ULReed
Start date: March 1, 2019
Phase:
Study type: Observational

Program Ready2E.A.T. was developed to be tested in the upper limb reeducation on population at risk, such as: - Children with dysfunction - Cognitive impaired elderly - Dementia people

NCT ID: NCT03986333 Completed - Cerebral Palsy Clinical Trials

Validation of the French Version of the Drooling Impact Scale in a Pediatric Cerebral Palsy Population

Start date: January 2015
Phase:
Study type: Observational

The aim of this study is to present the French translation of the Drooling Impact Scale (DIS-F) and to explore its validity, reliability and responsiveness to change in a group of children with Cerebral Palsy (CP)

NCT ID: NCT03979898 Completed - Cerebral Palsy Clinical Trials

Safety and Effectiveness of Autologous Adipose Tissue Derived Mesenchymal Stem Cell Implantation in Patients With CP

CP
Start date: June 15, 2017
Phase: Early Phase 1
Study type: Interventional

Safety and Effectiveness of Autologous Adipose Tissue Derived mesenchymal Stem Cell Implantation in Patients with CP

NCT ID: NCT03954808 Completed - Cerebral Palsy Clinical Trials

Motor Imagery Training in Children With Unilateral Cerebral Palsy

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Motor imagery (MI) is a promising method to improve more cognitive aspects of motor behaviour, and may, thus, be effective for facilitating motor planning in children with Cerebral Palsy (CP). MI training facilitates the neural plasticity by enhancing the neuronal cortical pathways in brain. In children with CP, motor planning and MI capacity were found to be affected by studies. In the literature, there are studies about the evaluation of MI in Unilateral CP but there is insufficient number of studies included in MI in the rehabilitation program. The aim of the study was to investigate the effect of motor imagery training for gait and lower extremity muscle activity (with EMG), functional capacity, quality of life, and time performance variables in Children with Unilateral CP. The eligible participants will be allocated three groups, including motor imagery training group, traditional physiotherapy control group, and healthy control group. All the assessments will be performed before and after the training in the 8-week motor imagery training group and 6 weeks after the end of training. The participants in the control group will be evaluated with a 8-week interval and 6 weeks after the end of physiotherapy training. The healthy participants will be assessed only once. The motor imagery training will be designed for the individual basis with standard protocols. It will be applied two times a week for 8 weeks. All sessions will be performed in the clinic.

NCT ID: NCT03951441 Recruiting - Cerebral Palsy Clinical Trials

Construct Validity and Reliability SCALE

Start date: October 9, 2017
Phase:
Study type: Observational

The aim of the study was to determine construct validity, discriminant validity and intra- and interrater reliability of the Selective Control Assessment of the Lower Extremity ( SCALE).

NCT ID: NCT03940989 Completed - Cerebral Palsy Clinical Trials

The Impact of Dosing Parameters on Motor Skill Acquisition and Retention in Bilateral Cerebral Palsy (BCP)

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

A recent systematic review found that therapeutic interventions that apply principles of motor learning with intense practice improve functional upper extremity movement in children with unilateral CP. Evidence of efficacy for any treatment approach aimed at improving motor function in bilateral CP (the most prevalent form) is lacking. Preliminary investigation suggests that intensive (90 hours) goal-directed, task-specific training provided in a 3-week day camp format can improve functional movement of both the upper (UE) and lower extremity (LE) and postural control in children with BCP. To date, HABIT-ILE has only been provided in a day camp setting over several weeks. Implementing the dosing schedule of this promising intensive approach in a hospital setting requires innovative resource allocation (space and staff); thus, examining alternative delivery models is imperative. The purpose of this study is to conduct a multi-center randomized control trial (RCT) to determine whether 90 hours of HABIT-ILE improves functional motor skills, activity and motivation in children with BCP when dosed in a camp format at 6-hours/day, 5 days/week for three weeks and 6-hours/day, one day/week for 15 weeks.