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Cerebral Palsy clinical trials

View clinical trials related to Cerebral Palsy.

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NCT ID: NCT00726206 Completed - Cerebral Palsy Clinical Trials

Correlation Between the Analysis of the Rapid Cortical Oscillations, the General Movements of the Preterm's and the Cerebral Palsy

Start date: July 2008
Phase: N/A
Study type: Interventional

The general movement and the electroencephalogram analysis of the preterm have a high predictive value of the neuro-developmental outcome of the infants.

NCT ID: NCT00717028 Completed - Cerebral Palsy Clinical Trials

Functional Endoscopic Evaluation of Swallowing

Start date: September 2005
Phase: N/A
Study type: Observational

The investigators objective is to describe functional endoscopic evaluation of swallowing findings in children with cerebral palsy.

NCT ID: NCT00680264 Recruiting - Cerebral Palsy Clinical Trials

Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy

PCPS
Start date: June 2008
Phase:
Study type: Observational

The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.

NCT ID: NCT00655681 Completed - Cerebral Palsy Clinical Trials

Prevention of Post Operative Bone Loss in Children

Start date: September 2007
Phase: N/A
Study type: Interventional

Hypothesis: one-dose pamidronate will prevent post-operative bone loss in children at risk for low bone density Plan: children with chronic disease such as CP, spina bifida, etc. will be recruited pre operatively and studied with DXA scan. After surgery, children will be randomized to receive either pamidronate or saline. Repeat DXA scan will determine bone lost after end of immobilization or nonweightbearing.

NCT ID: NCT00651339 Terminated - Cerebral Palsy Clinical Trials

The Effect of Botox Injection on Postural Stability of Cerebral Palsy (CP) Children

Start date: February 2008
Phase: N/A
Study type: Observational

Children suffer from Cerebral Palsy that willing to participate in the study will be tested with well-established measuring techniques of Balance control using force plate before 2 month after BOTOX injection in the movement and Rehabilitation Laboratory at BGU. An automated algorithm will be used to extract standardized stabilogram-diffusion parameters from each of the COP data sets collected during quiet standing. These parameters include diffusion coefficients, critical displacement, critical time and scaling exponents for both lateral and anterior-posterior sway directions (Collins & De Luca, 1993). Each of the Times (before 3 month and 6 month after the THA) in two task conditions (eyes closed and eyes close conditions). Participants will be required to stand on the platform 5 times for 30 s For each trial, they will be instructed to sway as little as possible. In addition Gait analysis will be also examined.

NCT ID: NCT00632528 Completed - Cerebral Palsy Clinical Trials

MEOPA to Improve Physical Therapy Results After Multilevel Surgery

KINOPA
Start date: March 2008
Phase: Phase 3
Study type: Interventional

Children with cerebral palsy commonly undergo "multilevel surgery", meaning several lower limb combined procedures performed during the same surgical intervention. The aim of this type of surgery is to correct all deformities together in order to restore near to normal anatomy and muscular function. It is very important to be able to obtain good range of motion after surgery, in order to consolidate surgical results. During the first days after the operation, children are sore and it may be difficult to realize adequate physical therapy. In order to palliate this situation, MEOPA gaz is used during REHAB sessions. Good results have been obtained so far but no study is available to demonstrate these results. The goal of our research is to prove that there is a benefit in using MEOPA postoperatively in these patients.

NCT ID: NCT00629070 Completed - Cerebral Palsy Clinical Trials

Quadriceps Muscle Plasticity in Children With Cerebral Palsy

Start date: January 2009
Phase: N/A
Study type: Interventional

Our primary aim is to determine whether and how muscle architecture of the quadriceps muscles in cerebral palsy (CP) adapts to two separate training programs: traditional strength training (ST) vs. velocity-enhanced training (VT). For the ST group, we hypothesize that muscle size will increase in conjunction with strength. For the VT group, in addition to the above, we hypothesize that fiber length will increase with measures of muscle power. We also hypothesize that walking velocity will improve in both groups but that knee motion and step length will improve only with VT.

NCT ID: NCT00619853 Completed - Clinical trials for Hemiplegic Cerebral Palsy

The Influence of MCIMT (Modified Constrained Induced Movement Therapy), Bilateral Intensive Treatment, and NDT Approach on the UL Function in Children With Hemiplegic Cerebral Palsy

CIMT
Start date: June 2007
Phase: Phase 2
Study type: Interventional

The purpose of this pilot study was to compare unimanual training (CIMT) and bimanual training (HABIT) protocols aimed to improve ability of the involved hand in children with hemiplegia. Both protocols were conducted in an educational setting for 2 hours a day for 2 months, one-hour group session and one-hour individual therapy session conducted by occupational therapists or assistants. The children in the CIMT group practiced various tasks using their involved hand with the contralateral hand constrained with a mitt. The children at the HABIT group practiced various bimanual tasks without constraint. Twelve children (2 - 6.5 yrs.) participated in this study. The inclusion criterion included minimal extension movement of the involved wrist, and for the CIMT group, the ability to of tolerates the mitt. The children were matched in relation to cognitive level and MACS score and randomly divided into the two intervention groups. Each child's assessment included the Quality of Upper Extremity Skills Test (QUEST), the Assisting Hand Assessment (AHA), and the Blocks and Box for children above age 5 yrs old. Range of motion (ROM) was assessed using an electronic gonimeter, and muscle tone was recorded using surface EMG and the Tardiue scale. The Child Health Questioner (CHQ) was completed by the parents before, and 6 months after, the intervention. Children were assessed starting two month before, and two month after, the intervention.

NCT ID: NCT00607542 Completed - Cerebral Palsy Clinical Trials

Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity

Best PK/PD
Start date: November 2008
Phase: Phase 1/Phase 2
Study type: Interventional

Oral baclofen is used commonly to treat spasticity in children with cerebral palsy. Although for adults there is dosing,safety and efficacy information in the package insert, this is not the case for children. The purpose of this study is to determine how fast the drug is cleared from the body, the correct dose, and long-term safety and efficacy for children with spasticity.

NCT ID: NCT00600717 Enrolling by invitation - Healthy Clinical Trials

Clinical Applications of High-Frequency Oscillations

HFOs
Start date: November 1, 2000
Phase:
Study type: Observational

The objective of this study is to use high-frequency brain signals (HFBS) to localize functional brain areas and to characterize HFBS epilepsy, migraine and other brain disorders. We hope to build the world's first high-frequency MEG/MEG/ECoG/SEEG database for the developing brain. HFBS include high-gamma activation/oscillations, high-frequency oscillations (HFOs), ripples, fast ripples, and very high frequency oscillations (VHFOs) in the brain. To reach the goals, we have developed several new MEG/EEG methods: (1) accumulated spectrogram; (2) accumulated source imaging; (3)frequency encoded source imaging; (4) multi-frequency analysis; (5)artificial intelligence detection of HFOs; (6) Neural network analysis (Graph Theory); and (7) others (e.g. ICA, virtual sensors).