Clinical Trials Logo
  1. Home
  2. Cerebral Blood Flow
  3. NCT04234009

Lifestyle and Brain Vascular Function

Healthy Lifestyle Clinical Trial

Official title:
The Effects of a Healthy Lifestyle Intervention on Brain Vascular Function in Older People

Clinical Trial Summary

Cognitive performance is negatively related to an impaired glucose metabolism, possibly due to impairments in brain vascular function. Supported by the statement from the American Heart and Stroke Association that a healthy lifestyle is one of the most effective strategies to protect against cognitive decline, the investigators now hypothesise that healthy lifestyle intervention-induced changes in glucose metabolism cause beneficial effects on brain vascular function thereby improving cognitive performance. The primary objective of this intervention study is thus to evaluate in sedentary older men and women the effect of a 16-week aerobic-based exercise program on cerebral blood flow, as quantified by the non-invasive gold standard magnetic resonance imaging (MRI) perfusion method Arterial Spin Labeling (ASL). Cerebral blood flow is a robust and sensitive physiological marker of brain vascular function. Secondary objectives are to examine effects on glucose metabolism using the homeostatic model assessment for insulin resistance (HOMA-ir) and cognitive performance as assessed with a neurophysiological test battery.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04234009
Study type Interventional
Source Maastricht University Medical Center
Contact
Status Terminated
Phase N/A
Start date January 22, 2020
Completion date December 1, 2020
View Details
See also
  Status Clinical Trial Phase
Completed NCT05109026 - Connect-5 Needs Assessment Survey to Identify Healthy Lifestyle Requirements of a Rural Irish Community
Completed NCT05510297 - Active Seating System to Lessen Sedentariness in Older Adults: In-home Testing Phase N/A
Completed NCT05483296 - Effects of Afternoon and Evening Light on Teenagers' Melatonin Levels, Alertness, Sleepiness and Sleep N/A
Not yet recruiting NCT05218980 - Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health N/A
Completed NCT04555746 - Active Kindergarten - Active Children N/A
Completed NCT01579708 - Evaluation of the Program SI! for Preschool Education: A School-Based Randomized Controlled Trial Phase 3
Completed NCT05273086 - The Effect of a Sleep Intervention on Sleep Quality in Nursing Students N/A
Recruiting NCT06022185 - E-Health Literacy, Digital Literacy, Healthy Lifestyle and Web Based Education for Young Old Individuals N/A
Not yet recruiting NCT06025019 - Effectiveness of Parent-based Electronic Health (eHealth) Intervention on Preschoolers' Physical Activity, Dietary Behaviors, and Sleep Problems N/A
Completed NCT05492162 - An Intervention to Promote Health Students' Well-being N/A
Not yet recruiting NCT05031377 - Effects of Cardiovascular Health Education Program on Community-dwelling Older Adults at Risk of ASCVD N/A
Completed NCT05002049 - Science Engagement to Empower Disadvantaged adoleScents (SEEDS Project) N/A
Active, not recruiting NCT05100953 - Application of Physical Activity Counseling Program N/A
Completed NCT04675658 - Stay Active Physical Activity Program N/A
Recruiting NCT04571775 - Effects of a Lifestyle Product on Physiological Measures and Subjective Well-being in Humans: A Systematic Study N/A
Recruiting NCT05891977 - Effect of Tomato Paste Consumption on the Microbiota-gut-brain Axis in Healthy Adults N/A
Active, not recruiting NCT05067816 - Med-South Lifestyle Program Implementation Study N/A
Enrolling by invitation NCT05974826 - Healthy Communities: A Healthy City Preventive Program on Cardiovascular Health and Well-being (HC) N/A
Recruiting NCT05653258 - Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects Phase 2/Phase 3
Recruiting NCT05858593 - Positive Youth Development in the Metaverse N/A