Total Corneal Astigmatism Prevalence in Cataract Patients

Cataract Clinical Trial

Official title:

Prevalence Data for Total Corneal Astigmatism in Cataract Surgery Candidates

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06148857
• Other study ID #: BLB2
• Status: Not yet recruiting
• Start date: November 2023
• Est. completion date: December 2023

Study information

• Verified date: November 2023
• Source: Peking University Third Hospital
• Contact: Hong Qi, Dr.
• Phone: +8613901066889
• Email: doctorgihong[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to report the prevalence data for total corneal astigmatism (TCA) in cataract surgery candidates.

Description:

The purpose of this retrospective study is to report the prevalence data for total corneal astigmatism (TCA) in cataract surgery candidates. Preoperative biometric data of all the patients who underwent cataract surgery in the Department of Ophthalmology, Peking University Third Hospital, from January 2019 to May 2023, were collected and analyzed. Data sets with incomplete biometric data were excluded.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 11000
• Est. completion date: December 2023
• Est. primary completion date: November 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients who underwent cataract surgery in the Department of Ophthalmology, Peking University Third Hospital from January 2019 to May 2023.

Exclusion Criteria:

• Incomplete biometric data .

Related Conditions & MeSH terms

• Astigmatism
• Cataract

Intervention

Diagnostic Test:
• IOLMaster 700
The IOLMaster 700, one of the most commonly used optical biometers for IOL power calculation, measures the anterior corneal surface radius using a telecentric keratometry. Additionally, it employs swept-source optical coherence tomography (SS-OCT) technology to simultaneously measures the posterior cornea surface radius and central corneal thickness (CCT). The AK formula, described by Abulafia et al., is a regression formula that calculates an estimated TCA using K astigmatism. The Barrett toric calculator uses an unpublished mathematical prediction method of TCA based on anterior corneal measurements.

Locations

Country	Name	City	State
China	Peking University Third Hospital	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking University Third Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	total keratometric astigmatism	Total keratometry is calculated based on the anterior and posterior corneal surface radius and CCT using the thick lens formula with the actual indices of refractions for air (1.000), cornea (1.376), and aqueous (1.336) by IOLMaster 700. Total keratometric astigmatism is taken as the TCA measured by IOLMaster 700.	At Enrollment
Primary	Abulafia-Koch formula total corneal astigmatism	The AK formula, described by Abulafia et al, is a regression formula that calculates an estimated TCA using K astigmatism.	At Enrollment
Primary	Barrett toric calculator total corneal astigmatism	The Barrett toric calculator uses an unpublished mathematical prediction method of TCA based on anterior corneal measurements. AL, ACD, LT, WTW, and K data by IOLMaster 700 were input into the Barrett toric calculator. The target refraction, incision surgically induced astigmatism (SIA), and incision location were all set as 0. The output net astigmatism was recorded as TCA predicted by the Barrett toric calculator.	At Enrollment