Cataract Clinical Trial
Official title:
Timing of Anti-vascular Endothelial Growth Factor（Anti-VEGF） Intravitreous Injections for Diabetic Macular Edema(DME) in Patients Undergoing Cataract Surgery
The investigators aim to evaluate how different timing of anti-VEGF intravitreous injections affect visual acuity (BCVA) in patients with diabetic macular edema who are undergoing cataract surgery; and to evaluate how different timing of anti-VEGF intravitreous affect OCT CSF thickness and total number of postoperative injections in patients with diabetic macular edema who are undergoing cataract surgery.
Cataract is very common in diabetic patients and can lead to significant vision loss and
disability without medical intervention. Diabetic patients, particularly those with diabetic
macular edema (DME), experience poorer visual outcomes after undergoing cataract surgery
compared to non-diabetics. An increased risk in the development of post-operative cystoid
macular edema and exacerbation of baseline DME is reported and this poses a significant
challenge in managing concomitant DME and visually-significant cataracts.
Goals of the study are to evaluate how different timing of anti-VEGF intravitreous injections
(before operation, intra-operation or after-operation) affect visual acuity (BCVA) in
patients with persistent diabetic macular edema who are undergoing cataract surgery; and to
evaluate how different timing of anti-VEGF intravitreous injections affect OCT CSF thickness
and total number of postoperative injections in patients with diabetic macular edema who are
undergoing cataract surgery.
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