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Cataract clinical trials

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NCT ID: NCT05100186 Not yet recruiting - Cataract Clinical Trials

The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1

Start date: November 1, 2021
Phase: Phase 4
Study type: Interventional

To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) compared to insertion 1-day post-op.

NCT ID: NCT05095194 Not yet recruiting - High Myopia Clinical Trials

Influence of Capsular Tension Ring on IOL-capsular Complex After Cataract Surgery in Patients With High Myopia: a Clinical Observation Based on SS-OCT

Start date: October 2021
Phase: N/A
Study type: Interventional

The IOL-capsular complex is formed after cataract surgery and intraocular lens (IOL) implantation.Early postoperative mechanical wrapping of the anterior and posterior capsules plays a significant role in preventing IOL decentration and tilt, as well as formation of the IOL-capsular complex which reduces the incidence of posterior cataract opacity. Capsular tension rings were first introduced in the early 1990s for loosening and tightening the lens bag and maintaining the equatorial contour of the bag after cataract surgery.Today, capsular tension rings of many different designs are in use.The capsular tension rings can be used in eyes with fragile and split zonular fibers, as well as pseudoexfoliation, high myopia, Marfan syndrome, mature cataract and lens subluxation.The capsular tension ring reduces the incidence of decentration and tilt of the IOL by reducing capsular contraction. In addition, multi-focus IOL implantation combine with capsular tension ring result in smaller high-order aberrations in our eyes compared to cataract surgery with multi-focus IOL implantation alone.For patients with high myopia, they often have a longer axial length and a larger capsule diameter, which reduces the rotational stability of the IOL and may lead to tilt ,decentration and displacement of IOL.Currently, there is no literature guidance to compare the results of cataract surgery combined with or without capsular tension ring implantation in patients with high myopia.Our hospital has Swept-source Optical Coherence Tomography ( SS-OCT,Casia2, TOMEY, Japan), which can accurately photograph the process of IOL capsule bending and the changes of lens position after cataract surgery. SS-OCT can be used to evaluate the influence of capsular tension ring on the dynamic changes of IOL-capsular complex in patients with high myopia after cataract surgery.

NCT ID: NCT05069753 Not yet recruiting - Bilateral Cataract Clinical Trials

Patient Reported Visual Satisfaction Following Same Day or Delayed Bilateral Cataract Surgery

CatquestCBS
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Cataract is currently the leading cause of visual impairment worldwide with age being the most common cause of lenticular opacification. As cataract surgery is the most commonly performed elective surgery worldwide, forecasts of an increasing number of elderly individuals make it clear that efficient and evidence based models for managing cataract in the future need to be implemented to manage the broadening gap between intervention and available resources. Bilateral cataract is currently treated using same day separate surgical procedures (immediate sequential bilateral cataract surgery (ISBCS) or on separate days (delayed sequential bilateral cataract surgery (DSBCS). Whether one approach is more ideal than the other is an ongoing debate. There is, however, a clear advantage of same day surgery on resource management. The primary purpose of this clinical study is to measure the patient reported satisfaction regarding vision in a group of 300 participants following either same day or delayed bilateral cataract surgery.

NCT ID: NCT05042856 Not yet recruiting - Cataract Clinical Trials

To Evaluate IOL Position, Clinical Outcome of PanOptix in High Myopic Cataract Patients

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

To evaluate IOL position, clinical outcome of PanOptix in high myopic cataract patients

NCT ID: NCT05028530 Not yet recruiting - Clinical trials for Age-related Cataract

Correlation Analysis of Lens Nucleus Density and Surgical Parameters Based on Ss-oct and Scheimpflug Technology

Start date: October 1, 2021
Phase:
Study type: Observational

To study the correlation between three different lens nuclear opacity classification methods and intraoperative phacoemulsification parameters .

NCT ID: NCT05023304 Not yet recruiting - Cataract Clinical Trials

In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery

Prepare
Start date: August 23, 2021
Phase: Phase 4
Study type: Interventional

To evaluate the clinical outcomes with optometrist pre-surgical insertion of DEXTENZA in the clinical office setting in patients undergoing same-day cataract surgery compared to standard of care steroid therapy.

NCT ID: NCT05011747 Not yet recruiting - Glaucoma Congenital Clinical Trials

Viscotrabeculotomy in Pediatric Glaucoma Following Cataract Surgery

Start date: September 2021
Phase: N/A
Study type: Interventional

Long term Surgical Outcomes of Viscotrabeculotomy in Pediatric Glaucoma Following Cataract Surgery. Purpose: This study aims to compare outcomes of single-site rigid probe viscotrabeculotomy (VT) to two-site VT in pediatric secondary glaucoma following cataract surgery. Methods: This is a comparative study was performed on patients aged ≤ 12 years and required surgery for glaucoma following congenital cataract surgery (GFCS) with or without intraocular lens (IOL) implantation. Eyes in which the trabeculotomy involves <180° of Schlemm's canal ,eyes that have synechial angle closure over ≥ 90° and eyes that have previous procedures other than lensectomy or IOL implantation are excluded from the study. Eyes are then randomized to undergo single-site VT or two-site VT using a random table. The two-site VT by the rigid probe trabeculotome is performed through a superonasal and an inferotemporal triangular scleral flap. Intraocular pressure (IOP), anti-glaucoma medications, complications and success rates at dates of follow up are all reported. Success is defined as IOP between 6-20 mmHg or 35% IOP reduction with or without topical anti-glaucoma medications and without visually-devastating complications or additional glaucoma surgery.

NCT ID: NCT04977427 Not yet recruiting - Macula Edema Clinical Trials

Dextenza vs Prednisolone Acetate After Cataract Surgery for Patients With Diabetes

Start date: July 2021
Phase: Phase 4
Study type: Interventional

This study aims to compare the effectiveness of Dextenza vs standard of care prednisolone taper after cataract surgery in diabetic patients with regards to controlling post-op inflammation at post-op days 7, 14, and 30.

NCT ID: NCT04977115 Not yet recruiting - Cataract Extraction Clinical Trials

Clinical Evaluation of Intraocular Caliper-assisted Capsulotomy for Age-related Cataract

Start date: July 26, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the accuracy of capsulotomy assisted by intraocular caliper and Verion navigation system in phacoemulsification surgery and postoperative visual quality of patients.

NCT ID: NCT04977102 Not yet recruiting - Cataract Extraction Clinical Trials

A Randomized Study of Intraocular Caliper-assisted Capsulotomy for Age-related Cataract Patients With Corneal Limbus Opacity

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the accuracy of capsulotomy assisted by intraocular caliper and Verion navigation system in phacoemulsification surgery and postoperative visual quality for age-related cataract patients with corneal limbus opacity.