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Cataract clinical trials

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NCT ID: NCT03933280 Completed - Conscious Sedation Clinical Trials

Conscious Sedation for Cataract Operations Under Topical Anaesthesia

Start date: July 1, 2019
Phase: Phase 2
Study type: Interventional

Topical anaesthesia of the eye for ophthalmologic procedures avoids pain and discomfort of local anaesthetic injection in the peribulbar or retrobulbar block so that patient comfortability is achieved. Sedation during topical anaesthesia of the eye is mostly required to achieve anxiolysis, amnesia and keeping the patient calm all through the procedure. In the present study, the investigators will investigate the effect of nalbuphine/dexmedetomidine versus nalbuphine/propofol on the sedation as a primary outcome, intra-operative, postoperative analgesia, vital signs, patient and surgeon satisfaction and side effects as secondary outcomes

NCT ID: NCT03931629 Completed - Cataract Clinical Trials

Study of the Efficiency and Workflow of Femtosecond Laser Assisted Cataract Surgery in a Spanish Public Hospital

FLACS
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Purpose: To assess the time-efficiency of a designated operation room (OR) workflow in the introduction of Femtosecond laser-assisted cataract surgery (FLACS, LenSx, Alcon®). The study was carried out in a public hospital with high volume of procedures. Setting: Ophthalmology department of a tertiary referral Spanish public hospital. Design: Prospective, controlled, surgical intervention study. Methods: A total of 167 eyes were enrolled, including 62 eyes undergoing conventional phacoemulsification surgery. In phase I, patients were assigned either to FLACS-I (n=63) or conventional phacoemulsification surgery (n=62). One surgeon operated the Femto-second laser, another finished the procedure, whereas another performed a conventional phacoemulsification. In the second phase (FLACS-II), all the surgeries were FLACS (n=42). A surgeon performed the FLACS procedure and two different surgeons completed the surgeries in separated ORs. Surgical and roll-over times of all the patients were recorded.

NCT ID: NCT03925545 Completed - Cataract Clinical Trials

VisiOn Restoration With FluidVisION Accommodating Intraocular Lens (AIOL)

ORION
Start date: January 17, 2017
Phase: N/A
Study type: Interventional

The objective of this study is to obtain an initial assessment of the safety and performance of an investigational AIOL in patients undergoing cataract extraction and IOL implantation.

NCT ID: NCT03923283 Completed - Clinical trials for Other Disorders of the Eye Following Cataract Surgery

The Measurements of End-tidal Carbondioxide Levels

Start date: January 1, 2016
Phase:
Study type: Observational

Purpose: The aim of this retrospective study is to investigate the end tidal carbon dioxide pressure (ETCO2) values in order to determine the carbon dioxide accumulation under drape and to investigate it's hemodynamic effects based on anesthetic and surgical records in eye surgeries under local anesthesia. Methods: The data were collected from anesthetic records of the patients who were followed with noninvasive capnograph (Capnostream 20 p, Oridion®, Israel) by the anesthesiology department in the operating room at Duzce University Faculty of Medicine Hospital during the period of January 2016 to December 2016. Collected data from the 42 patients' records were systolic, diastolic and mean arterial pressures, operation duration, total local anesthetic and, heart rate, ST segment analysis, ETCO2 pressure, pulse oximeter values. The time periods of collected datas were determined as: after the anesthesia and before drape closure (baseline level), at 10th, 15th, 20th, 45th of the surgery and 5 minutes after drape removal.

NCT ID: NCT03923244 Completed - Dry Eye Syndrome Clinical Trials

Dry Eye Syndrome Description During Cataract Surgery, With Multimodal Analysis of the Ocular Surface

C-SS0
Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The main objective is to describe the characteristics of dry eye syndrome before and after surgery at one month of cataract surgery, using a multimodal analysis of the ocular surface. The secondary objectives are to evaluate: - Predictive factors of dry eye syndrome during cataract surgery: - The characteristics of dry eye syndrome - Implications for the patient's quality of life

NCT ID: NCT03905044 Completed - Congenital Cataract Clinical Trials

Clinical Characteristics in Congenital Cataract Eyes

Start date: January 1, 2011
Phase:
Study type: Observational

This study involved children with congenial cataract eyes, who underwent cataract surgeries at the Eye Hospital of Wenzhou Medical University (Hangzhou, China). All medical records were reviewed for primary diagnosis. All surgeries were performed by one experienced surgeon (Z.Y.E) and videos were collected for reviews in details. the clinical data after the surgery were also recorded for further analysis.

NCT ID: NCT03903965 Completed - Clinical trials for Diabetes Mellitus Type 2

Comparison of Retinal Perfusion Between Diabetic and Non-diabetic Patients With OCT Angiography After Cataract Surgery.

Start date: September 1, 2018
Phase:
Study type: Observational [Patient Registry]

This study aims to compare the retinal perfusion between diabetic and non-diabetic patients with Optical Coherence Tomography(OCT) Angiography after cataract surgery, to thoroughly evaluate the retinal state of diabetics after surgery, and to find out the relationship between postoperative complications occurred in retina and diabetes.

NCT ID: NCT03895034 Completed - Cataract Clinical Trials

Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes

Start date: June 14, 2018
Phase:
Study type: Interventional

The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments of the LAL with the LDD. This is an exploratory study. No primary effectiveness endpoints will be identified.

NCT ID: NCT03889652 Completed - Cataract Clinical Trials

Optical Coherence Tomography of Nerve Fiber Layer and Ganglion Cell Complex After Cataract Extraction

Start date: October 20, 2018
Phase:
Study type: Observational

Optical coherence tomography (OCT) for retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) is done before and after cataract extraction in patients with or without primary open angle glaucoma (POAG)

NCT ID: NCT03886779 Completed - Clinical trials for Treatment of Ocular Inflammation Associated With Cataract Surgery

Study Title: Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (Nepafenac Ophthalmic Suspension) 0.3% QD With Extra (Pulse) Dose on Day of Surgery for Treatment of Ocular Inflammation Associated With Cataract Surgery in a Randomized, Single Masked Clinical Trial

Start date: October 30, 2013
Phase: Phase 4
Study type: Interventional

Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (nepafenac Ophthalmic Suspension) 0.3% QD with extra (pulse) dose on day of surgery for Treatment of Ocular Inflammation Associated with Cataract Surgery