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Cataract clinical trials

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NCT ID: NCT03584893 Recruiting - Clinical trials for Cerebrotendinous Xanthomatosis

The Prevalence of CTX Disorder in Juvenile Cataract Cases in Turkey

GEN-EYE-I
Start date: June 1, 2018
Phase:
Study type: Observational

Epidemiologic observational study. Study will include two phases: 1. Retrospective cross-sectional phase: At this stage of the study, retrospective screenings are carried out at study sites and all juvenile cataract cases are planned to be determined. 2. Prospective phase: At this stage of the study, identified juvenile cataract cases as a result of retrospective screenings will be called to be invited to the sites and blood samples will be obtained for the cholestanol tests for the cases that have given Informed Consent. This observational study is designed in two phases; retrospective and prospective. Retrospective part includes screening the patient database and / or patient files at ophthalmology clinics participating in the study and identifying patients diagnosed with idiopathic juvenile cataracts. The data of patients with idiopathic juvenile cataracts will be reviewed and the data of the patients meeting the inclusion/exclusion criteria will be recorded. Once this phase is completed, the prospective phase of the study will start and the patients meeting the criteria will be invited to the site to participate in the study. Current data will be collected from the patients who agree to participate in the study and the clinical status of the patients will be evaluated according to the Mignarri index. In addition, blood will be obtained from all patients to diagnose CTX disease. Blood samples will be sent to Duzen Laboratories in Ankara and analyzed for cholestanol.

NCT ID: NCT03564990 Recruiting - Congenital Cataract Clinical Trials

The Impact of Interactive, Multifaceted Approach Education on Congenital Cataract

Start date: June 30, 2018
Phase: N/A
Study type: Interventional

To evaluate the impact of a health education program on parental anxiety, the comprehension-memorization of the information and their satisfaction.

NCT ID: NCT03538964 Recruiting - Cataract Clinical Trials

Assessing the Astigmatism Reducing Effect With Toric IOLs in Eyeswith Low Astigmatism

Low Asti
Start date: May 2, 2018
Phase: N/A
Study type: Interventional

Comparison of the astigmatism reducing effect of a toric IOL with a non toric IOL in eyes with low corneal astigmatism.

NCT ID: NCT03534973 Recruiting - Cataract Clinical Trials

Prevention of UV- Induced Apoptosis by Caffeine

Caff2
Start date: April 17, 2018
Phase: N/A
Study type: Interventional

Investigate if caffeine accumulation in human lens epithelial cells after oral caffeine intake is sufficient to prevent from experimental ultraviolet radiation induced apoptosis

NCT ID: NCT03525015 Recruiting - Clinical trials for Age Related Cataracts

Impact of a Printed Decision Aid on Cataract Surgery Choice

Start date: May 16, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to explore whether a decision aid booklet is more effective than the usual booklet for patients to make an informed choice on cataract surgery.

NCT ID: NCT03485586 Recruiting - Clinical trials for Diabetic Retinopathy Patients After Vitrectomy

Comparison of the Visual Quality of Traditional Ultrasound Biometrics and Lenstar on the Cataract After Pars Plana Vitrectomy

PPV
Start date: April 3, 2018
Phase:
Study type: Observational

Comparison of the visual quality of traditional ultrasound biometrics and lenstar on the cataract patients with diabetic retinopathy after vitrectomy in the 3 months later.To evaluate the clinical value of lenstar in post-vitrectomy patients.

NCT ID: NCT03455478 Recruiting - Clinical trials for Blindness,Visual Impairment, Refractive Error, Cataract, High Myopia, Aging

Shanghai Eye Study for Adults

SESA
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Blindness and visual impairment severely impact the visual health and life quality of people, particularly the 2.566 million senior citizens aged at 65 and above in Shanghai. The main reason is uncorrected refractive error, of which, 62.1% can be solved through refractive correction. For this reason, the uncorrected refractive errors of 154,000 senior citizens in Shanghai can be taken as a priority among the public health issues to prevent blindness. Now, with the aim to reduce the prevalence rate of blindness and visual impairment, it is planned to establish a public health service mechanism in terms of refractive error screening and correction for the elderly by relying on Shanghai's three-level (city-district-community) eye diseases prevention network, using proper refractive correction technology, and moving related services forward to communities in order to screen, identity, and correct blindness and visual impairment caused by refractive errors as early as possible.

NCT ID: NCT03417453 Recruiting - Cataract Clinical Trials

Eye Drop Dispensers: Safety, Efficacy and Comfort.

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

One aspect to eye drop adherence is successful instillation of the drops; however, it is well known that many patients struggle with this task. Difficulties may include aiming their drops,extending their neck, preventing excess drop leakage, avoiding contamination of the bottle tip and generating enough force to expel a drop from the bottle. Instillation aids are devices that aim to ameliorate one or more of these barriers. Several eye drop dispensers had been developed in order to improved outcomes of eye drop instillation, including improved rates of successful administration and increased patient satisfaction compared to standard eye drop bottles. In this study we aim to compare the eye drops various installation aids

NCT ID: NCT03375996 Recruiting - Cataract Surgery Clinical Trials

Evaluation of a Protocol of Pupil Dilation Before Laser-assisted Cataract Surgery

MYFLACS
Start date: June 1, 2018
Phase:
Study type: Observational

Laser-assisted cataract surgery is an innovative and growing procedure to improve the safety and results of modern cataract surgery. However, this technique faces to some obstacles: economics in the one hand due to the cost and time spent for the laser procedure before the conventional surgery, and technical in the other hand, especially due to some loss of pupil dilation during the surgery, which is highly important to ensure a perfect procedure. The present study aims at assessing a pharmacological protocol to maintain an accurate pupil dilation all along the surgery in order to improve the whole procedure.

NCT ID: NCT03342794 Recruiting - Congenital Cataract Clinical Trials

Morphologic and Biometric Characteristics of Preexisting Posterior Capsule Defects in Congenital Cataracts During the First Year of Life

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Few descriptive studies have focused on the anatomical parameters in patients with preexisting PCDs. The characteristics of cataract morphology and anatomical parameters in these patients remained unclear, when compared with CC patients with intact posterior capsule. We conduct the current study to compare the cataract morphology and preoperative parameters, including central corneal thickness, axial length, anterior chamber depth, lens thickness, corneal diameter, keratometry,dialated pupil diameter and intraocular pressure, between CC patients with preexisting PCDs and those with intact posterior capsule, and to explore potential risk factors for preexisting PCDs.