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Cataract clinical trials

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NCT ID: NCT04200651 Terminated - Cataract Clinical Trials

Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery

SUSTAIN
Start date: January 13, 2020
Phase: Phase 4
Study type: Interventional

In this study, the investigators are comparing dexamethasone ophthalmic insert (DEXTENZA®) to the current standard of care, prednisolone acetate 1% eye drops, in a glaucoma population receiving both cataract and minimally-invasive glaucoma surgery (MIGS). DEXTENZA® and prednisolone acetate 1% drops are both steroids used to control inflammation after eye surgery. DEXTENZA®'s method of delivery differs by offering a sustained release of steroid that does not necessitate postoperative anti-inflammatory eye drops. The investigators hypothesize that DEXTENZA® will be as safe as prednisolone acetate 1% drops and as effective at controlling postoperative inflammation following concomitant cataract-MIGS in a glaucoma population. The investigators also hypothesize that DEXTENZA® will be preferred by patients over prednisolone acetate 1% drops.

NCT ID: NCT04128514 Terminated - Cataract Clinical Trials

Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens

Start date: October 11, 2019
Phase:
Study type: Observational

The study was designed to assess the spectacle independence and satisfaction of patients receiving the AcrySof® Panoptix® Toric intraocular lens (IOL) after uneventful cataract surgery.

NCT ID: NCT03778528 Terminated - Cataract Clinical Trials

Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome

Start date: May 30, 2018
Phase:
Study type: Observational

This study involves the collection ocular lens tissue from individuals with Down syndrome and age-matched controls at the time of cataract surgery.

NCT ID: NCT03640650 Terminated - Cataract Surgery Clinical Trials

Economic Impact of Dropless Therapy Versus Usual Care for Cataract Surgery: A Real-World Study.

Start date: August 15, 2018
Phase: Phase 4
Study type: Interventional

This real-life Health Economics and Outcome Research (HEOR) study will enable to evaluate the economic impact of Dropless therapy for the prophylactic treatment of inflammation and infection after routine cataract surgery. This prospective randomized controlled crossover open-label study will estimate resource utilization and cost attributable to patients' management following a cataract surgery and until last follow-up visit and adherence, satisfaction and preference between usual care and Dropless in a real-life setting. Data collected will include patients' characteristics and demographics, medical information, cataract surgery information, healthcare resource utilization, patients' adherence to topical ophthalmic medications as well as patients' satisfaction to both treatment and preference between usual care and Dropless. Patients will fill a set of questionnaires at their recruitment in the study and at their last follow-up visit for their two cataracts surgery.

NCT ID: NCT03596723 Terminated - Ocular Inflammation Clinical Trials

KPI-121 1% Versus Prednisolone for the Treatment of Inflammation Following Cataract Surgery in Children

Start date: July 3, 2018
Phase: Phase 3
Study type: Interventional

This study is designed to assess how KPI-121 1% compares to prednisolone acetate in reducing inflammation after cataract surgery in young children. Approximately half the participants will receive KPI-121 1% eye drops and the other half will receive prednisolone acetate.

NCT ID: NCT03454334 Terminated - Cataract Clinical Trials

Visual Performance of Four Types of Multifocal Intraocular Lenses

presbyopia
Start date: August 11, 2013
Phase: N/A
Study type: Interventional

This investigation assessed the visual performance of presbyopia and cataract patients after bilateral implantation of 4 distinct sorts of multifocal IOLs: At lisa tri, PanOptix, ReSTOR, and Symfony. The clinical results demonstrated here were excellent for four groups, however, there were also differences in group ReSTOR, UCVA and BCVA for the intermediate and near of the other groups showed less vision also symphony group for far distance demonstrated less vision than other groups, which may be related to their design.Multifocal IOLs demonstrated very good technology and unquestionably have a place in refractive surgery, whether for clear lens extraction or cataracts.Patients can expect excellent outcomes and surgeons can expect patients to be very satisfied with surgical outcomes. Four groups multifocal lenses provided excellent distance, intermediate and near vision, but several measures indicated that the PanOptix and at lisa tri lens provided better vision in all distances. Spectacle independence was significantly higher with four groups. Multifocal IOL design might play a role in the postsurgical outcome, because better results were obtained with diffractive lenses. Although there were differences in the results of these four lenses in the study, all of the results were acceptable.

NCT ID: NCT03409185 Terminated - Cataracts Clinical Trials

The Incidence of Glistenings in the 2017 Intraocular Lenses Made by Alcon and Abbott Medical Optics

Start date: July 11, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to seek academic/non-industry research funding support to independently investigate the incidence and density of lens glistenings in cataract patients who are implanted with the latest generations of intraocular lenses (IOL) manufactured by Alcon and AMO Medical Optics.

NCT ID: NCT03401606 Terminated - Clinical trials for Failed Conscious Sedation During Procedure

Controlled Sedation for Cataract Surgery

Start date: November 1, 2014
Phase: Phase 4
Study type: Interventional

This study evaluates the surgeon and patient´s satisfaction who undergoes cataract surgery using either dexmedetomidine or remifentanil as sedation

NCT ID: NCT03273907 Terminated - Cataract Clinical Trials

Post Approval Study of the CyPass System

Start date: October 12, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate that the rate of clinically relevant complications associated with CyPass Micro-Stent placement and stability using the CyPass 241-S applier, as determined at 36 months in the postmarket setting, is less than the pre-specified performance target, which is based on experience with the CyPass Model E applier in COMPASS trial TMI-09-01 (NCT01085357).

NCT ID: NCT03179397 Terminated - Cataract Clinical Trials

Clinical Trial to Evaluate the Model SC9 IOL Compared to the Model LI61SE IOL (Bausch & Lomb)

Start date: May 31, 2017
Phase: N/A
Study type: Interventional

To evaluate the Model SC9 Intraocular Lens for the improvement of near and intermediate vision when compared to a legally marketed monofocal IOL.