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Cataract clinical trials

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NCT ID: NCT05290870 Enrolling by invitation - Cataract Clinical Trials

Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.

Start date: February 1, 2022
Phase:
Study type: Observational

This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.

NCT ID: NCT04913792 Enrolling by invitation - Cataract Clinical Trials

Visual Performance of Multifocal Intraocular Lenses

Start date: November 1, 2016
Phase:
Study type: Observational

To evaluate the clinical outcomes with an extended range of vision (ERV) IOL based on achromatic diffractive technology.

NCT ID: NCT04670237 Enrolling by invitation - Cataract Clinical Trials

Clinical Outcome After Implantation of Medicontur Liberty 677MTY, a Multifocal, Toric IOL

Start date: December 1, 2019
Phase:
Study type: Observational

The purpose of this study is to evaluate visual outcomes, patient satisfaction and YAG capsulotomy rate after implantation of a multifocal toric lens- Liberty 677MTY - manufactured by Medicontur Ltd. (Zsámbék, Hungary),

NCT ID: NCT04660006 Enrolling by invitation - Cataract Clinical Trials

Diabetic Retinopathy and OCT-A Changes Post-cataract Surgery

Start date: May 27, 2019
Phase:
Study type: Observational

The purpose of this study is to use optical coherence tomography angiography (OCT-A) to compare retinal vasculature after uncomplicated cataract surgery in patients with and without diabetic retinopathy.

NCT ID: NCT04590651 Enrolling by invitation - Cataract Clinical Trials

Cataract Surgery in Patients With Pseudoexfoliation and Pseudoexfoliation Glaucoma

PHACOPXG
Start date: September 11, 2020
Phase: N/A
Study type: Interventional

The study aims to document the effect cataract surgery has on the pseudoexfoliation and pseudoexfoliation glaucoma eye. Details such has patient history, history of possible glaucoma, intraocular pressure, status of the eye, operation parameters and postoperative effect will be documented. The study is prospective and randomised . Patients will be divided in to two groups: in one standard phacoemulsification cataract surgery will be preformed. In the second group the anterior chamber angel will be aspirated an extra minute at the end of the case with the IA probe. The aim is to determine weather this extra aspiration will have an effect on postoperative intraocular pressure and other parameters.

NCT ID: NCT04499768 Enrolling by invitation - Clinical trials for Diabetic Retinopathy

A Longitudinal Study of Choroidal Changes After Cataract Surgery in Eyes With Diabetic Retinopathy

Start date: June 1, 2018
Phase:
Study type: Observational

To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery

NCT ID: NCT04342052 Enrolling by invitation - Glaucoma Clinical Trials

Glaucoma After Congenital Cataract Surgery

Start date: January 1, 2011
Phase:
Study type: Observational

To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.

NCT ID: NCT04104256 Enrolling by invitation - Clinical trials for Pre-Operative Testing for Cataract Surgery

Using Behavioral Economics to Reduce Low-Value Care

Start date: June 24, 2021
Phase: N/A
Study type: Interventional

There is strong consensus - based on robust randomized trial data - that routine pre-operative (pre-op) testing for cataract surgery is inappropriate. Despite these widely endorsed evidence-based recommendations, most seniors undergoing cataract surgery still receive unnecessary blood testing, EKGs, and chest X-rays (CXRs); another substantial percentage even undergo nonindicated cardiac stress tests. We will integrate three new best practice alert (BPA) nudges into the University of California, Los Angeles (UCLA) Health electronic health record (EHR). The nudges are informed by behavioral economic theory and are designed to alter the choice architecture for physicians to decrease the rate of pre-op test ordering while still preserving clinician autonomy. We will conduct a pragmatic trial to evaluate whether these BPA nudges reduce low-value pre-op testing for cataract surgery.

NCT ID: NCT04047485 Enrolling by invitation - Dementia Clinical Trials

Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients

Start date: February 2, 2019
Phase:
Study type: Observational

The study intends to measure the evolution over time of the cognitive capacity of patients undergoing cataract surgery in relation to the opaque lens removal surgery (cataract) in a population considered to be at risk of neurocognitive degeneration. Secondary objectives: • Estimate the incidence of postoperative cognitive dysfunctions and any episodes of perioperative delirium with the aim of demonstrating the safety of cataract surgery in the elderly patient in terms of cognitive functions and impact on the psychological state. In the context of the study a risk sub-population analysis will be carried out, evaluating the trend over time of the "endothelial cells count" parameter The elderly population remains, due to the aging of the cornea, a population "at risk" for significant alterations from the clinical point of view. During the study the endothelial cells count will be monitored, in order to be able to evaluate the safety of the cataract surgery and to be able to correctly correlate a possible deterioration in the visual acuity of patients with corneal decompensation. To evaluate the progress of the endothelial cells count in the elderly patient during the pre-intervention and post-intervention period. Since the low values of cellular media in endothelial microscopy are an element that increases the risk of complications during cataract surgery, the study wants to assess how waiting times between filter visits and cataract surgery can cause an elderly patient worsening of this parameter even in a few months. The trend of the same parameter will be monitored even after the intervention since in case of decrease, the low endothelial count could cause an alteration of visual acuity and therefore a minor improvement in cognitive performance. The research will be set as a longitudinal observational study where will be compared in each patient the parameters analyzed in the 6 months prior to cataract surgery and in the 3 months following the operation itself. Patients will be enrolled during the first cataract filter visit, will be submitted to simple questions and their clinical data will be collected. Subsequently, before and after three months of surgery repeated cognitive testing and the control normally performed instrumental tests during follow-up. A clinical follow-up will be provided, during normal follow-up visits at 20 days and 6 months after the patient's surgery: the following information will be collected during these visits - BCVA (visual acuity) - endothelial cells microscopy - OCT macula and optic nerve - Catquest 9SF; - Barthel Index; - Six Item Cognitive Test - Confusion Assessment Method (CAM): this exam will be performed within 24 hours of post-surgery and 20 days after surgery. It is important to underline that the cognitive tests proposed to patients consist of simple questions that do not depend on the visual ability of the subject.

NCT ID: NCT03831984 Enrolling by invitation - Cataract Clinical Trials

Topical Bromfenac for Intraoperative Miosis and Pain Reduction

Start date: March 1, 2018
Phase: Phase 4
Study type: Interventional

To evaluate the effect of bromfenac ophthalmic solution 0.09% for reduction of intraoperative miosis and pain in patient who have undergone femtosecond laser-assisted cataract surgery.