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Cataract clinical trials

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NCT ID: NCT04940793 Completed - Cataract Clinical Trials

Visual and Refractive Outcomes of a New Diffractive Trifocal Toric Intraocular Lens

RibeiroPODFT
Start date: July 18, 2017
Phase:
Study type: Observational

The purpose of this study is to investigate the visual performance and refractive predictability with the diffractive toric Finevision POD FT IOL. Predicted and achieved visual outcomes, visual performance at near, intermediate and far distance as well as photic phenomena, rotational stability and spectacle independence will be investigated. The follow-up period is 3 months after which vision and refraction should have stabilized.

NCT ID: NCT04940338 Completed - Clinical trials for Cystoid Macular Edema Following Cataract Surgery

PCME Prevention in Patients With NPDR

Start date: May 1, 2021
Phase: Phase 4
Study type: Interventional

Pseudophakic cystoid macular edema (PCME), or Irvine-Gass syndrome, is retinal thickening of the macula, which usually develops within 3 months after surgery, with a peak incidence between 4 and 6 weeks. Despite recent improvements in surgical techniques, PCME remains one of the most common causes of visual decline following an uneventful cataract surgery. Symptoms of PCME usually are blurred vision, metamorphopsia, loss of contrast sensitivity, and central scotomas. PCME usually responds well to medical therapy or may resolve spontaneously but carries a risk of permanent vision loss or loss of contrast sensitivity. There is wide discrepancy in opinions about the most effective antiinflammatory drops for the prevention of PCME. Patients with diabetes mellitus (DM) have attracted special interest because of higher incidence of cataract and increased risk for developing CME after cataract surgery. The optimum antiinflammatory prophylaxis for PCME in patients with nonproliferative diabetic retinopathy (NPDR) remains unknown. Purpose of this study is to determine the efficacy of topical bromfenac and topical dexamethasone on intraocular concentration of interleukin-6 (IL6) and the incidence of pseudophakic cystoid macular edema (PCME) after cataract surgery in patients with nonproliferative diabetic retinopathy (NPDR).

NCT ID: NCT04936256 Completed - Cataract Clinical Trials

Evaluation of Binocular Visual Acuity and Refractive Stability in the Alcon Clareon Intraocular Lens

Start date: July 2, 2021
Phase:
Study type: Observational

The objective is to evaluate refractive stability (spherical equivalent change ≤ 0.50D from 1-month to 3-months).

NCT ID: NCT04935541 Completed - Geriatrics Clinical Trials

Dexmedetomidine vs. Remifentanil Undergoing Cataract Surgery in Geriatrics

Start date: March 2009
Phase: N/A
Study type: Interventional

Dexmedetomidine is an α2-adrenergic receptor agonist used for its sympatholytic effect, providing sedation, analgesia, and cardiovascular stabilization in the perioperative period. Remifentanil is a µ opioid agonist with a rapid onset and short duration of action, which is degraded by plasma esterase in tissues. Investigators aimed to compare the effects of dexmedetomidine and remifentanil infusions on sedation quality, side effects, and surgeon's satisfaction in geriatric outpatients who underwent cataract surgery.

NCT ID: NCT04933487 Completed - Cataract Clinical Trials

Rotational Stability Analysis of a Toric Monofocal IOL

PHY2013
Start date: August 26, 2014
Phase: N/A
Study type: Interventional

This is a single-center, prospective PMCF study whereby patients undergoing routine cataract surgery will have monolateral implantation of hydrophilic monofocal toric intraocular lens Ankoris.

NCT ID: NCT04931277 Completed - Clinical trials for Outcome of Stepped Cataract Surgery in Uveitis

Stepped Surgery in Uveitic Cataract: A Novel Approach to a Quiet Eye

Start date: February 8, 2021
Phase: N/A
Study type: Interventional

This study aims to assess the short-term results of primary phacoemulsification and secondary posterior chamber intraocular lens (PCIOL) implantation in patients with uveitis.

NCT ID: NCT04924231 Completed - Cataract Clinical Trials

Effect of 1.8-mm Steep-axis Clear Corneal Incision on the Posterior Corneal Astigmatism in Candidates for Toric IOL Implantation

Start date: February 1, 2017
Phase:
Study type: Observational

we aimed to analyze the effects of cataract surgery using a 1.8-mm steep-axis clear corneal incision (CCI) on the posterior corneal surfaces based on the keratometry from the rotating Scheimpflug imaging device (Pentacam HR) in candidates for toric intraocular lens (IOL) implantation

NCT ID: NCT04907500 Completed - Cataract Senile Clinical Trials

Prospective Evaluation of an Hydrophilic Acrylic Intraocular Lens

UVEA 809
Start date: June 22, 2021
Phase: N/A
Study type: Interventional

Evaluation of the clinical safety and effectiveness of an hydrophilic acrylic intraocular lens

NCT ID: NCT04907318 Completed - Cataract Clinical Trials

Comparison Between a Toric Monofocal and Multifocal Intraocular Lens

Start date: January 1, 2016
Phase:
Study type: Observational

The primary objective of the study is to observe the rotational stability of the implant 30 minutes, one day, 6 weeks, 6 months and 12 months after the implant surgery. In addition, the refraction will be measured as it is directly affected in the event of postoperative rotation. The correlation between postoperative rotation and the following parameters will be determined: PEXS, white-to-white, age, axial length, anterior chamber depth. Visual acuities with and without correction and the best refraction to assess the benefit of the implants will also be investigated.

NCT ID: NCT04890249 Completed - Cataract Clinical Trials

Clinical Investigation of Two Tecnis Investigational Lenses

Start date: June 23, 2021
Phase: N/A
Study type: Interventional

This study is a 6-month, prospective, multicenter, randomized (1:1:1), subject-masked and evaluator-masked, bilateral clinical investigation of the TECNIS IOL Models C1V000 and C2V000 versus the TECNIS Eyhance™ Model ICB00 IOL. The study will be conducted at up to 15 sites in EU, AU, NZ and/or AP and will enroll up to 225 subjects to achieve approximately 67 bilaterally implanted subjects in each lens group. Allowing for 10% lost-to-follow-up, this will achieve approximately 60 evaluable subjects in each lens group at 1, 3, and 6 months. The eye implanted first will be considered the primary (monocular) study eye.