Dexmedetomidine vs. Remifentanil Undergoing Cataract Surgery in Geriatrics

Status Completed

Clinical Trial Summary

Dexmedetomidine is an α2-adrenergic receptor agonist used for its sympatholytic effect, providing sedation, analgesia, and cardiovascular stabilization in the perioperative period. Remifentanil is a µ opioid agonist with a rapid onset and short duration of action, which is degraded by plasma esterase in tissues. Investigators aimed to compare the effects of dexmedetomidine and remifentanil infusions on sedation quality, side effects, and surgeon's satisfaction in geriatric outpatients who underwent cataract surgery.

Clinical Trial Description

Dexmedetomidine is an α2 agonist and remifentanil is a short-acting μ, opioid agonist. The aim of this study was to compare dexmedetomidine and remifentanil infusions used for conscious sedation in geriatric patients undergoing outpatient cataract surgery in terms of sedation quality, hemodynamic stability, and surgeon satisfaction. Eighty patients were divided into two groups according to the administration of dexmedetomidine (Group D) and remifentanil (Group R) infusion in this randomized, prospective, double-blinded study. In group D (n = 40), after a loading of 1 µg/kg dexmedetomidine in 10 minutes, 0.4 µg/kg/h-1 infusion was administered. In Group R (n = 40), remifentanil at a dose of 0.05 µg/kg-1 was administered for 10 minutes, and then 0.05 µg/kg/min-1 infusion was continued. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04935541
Study type	Interventional
Source	Selcuk University
Contact
Status	Completed
Phase	N/A
Start date	March 2009
Completion date	July 2010

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02558907` - Comparison of MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment) in Cognitive Assessment in Geriatric Oncology	N/A
Completed	`NCT05197127` - Efficacy of Samsung GEMS-H Device Training in Older Adults	N/A
Not yet recruiting	`NCT06267833` - The Effect of Trunk and Upper Extremity Exercises Added to the Otago Exercise Program	N/A
Completed	`NCT04577092` - Dual Task Training for Balance in Older Adults	N/A
Completed	`NCT03188211` - E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF	N/A
Recruiting	`NCT05605392` - Live Better at Home, Navarra ( VMNav )	N/A
Completed	`NCT04069962` - Effectiveness of CGA on QoL in Older Patients With Cancer Receiving Systemic Therapy	N/A
Recruiting	`NCT02377908` - European Postgraduate Training in Geriatric Medicine	N/A
Completed	`NCT04171752` - Elafibranor Pharmacokinetic Parameters in Elderly Healthy Volunteers	Phase 1
Not yet recruiting	`NCT05567965` - Live Better at Home in Catalonia	N/A
Withdrawn	`NCT04010136` - Identification of Elderly Patients in Need of Palliative Care by Family Physicians	N/A
Not yet recruiting	`NCT06300281` - Comparison of Neuromuscular and Aquatic Exercise Programs on Fall Risk and Physical Function in Geriatrics	N/A
Completed	`NCT05400850` - YOGA Asanas and Myofascial Chain Activity in Elderly Individuals	N/A
Completed	`NCT02118259` - Impact of Multidisciplinary Review of Drug Prescriptions on Patient Safety in a Residence for Dependent Elderly	N/A
Completed	`NCT06209944` - Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong
Completed	`NCT06189430` - Effect of Vinyasa Yoga on Frailty and Anthropometric Measurements in Elderly Individuals	N/A
Withdrawn	`NCT02398851` - TacTIC- Trans-disciplinary Chronic Disease Continuity of Care Model	N/A
Recruiting	`NCT02604563` - Aging, Geriatric Syndromes and Clonal Hematopoiesis
Recruiting	`NCT05939531` - Multi-domain Intervention Program for Post-stroke Bone Health in Older Adults (BOUNCE)	N/A
Completed	`NCT05767372` - Effect of Coherent Breathing on Elderly Quality of Life	N/A