Cataract Extraction Clinical Trial
Official title:
Randomized, Controlled, Double-Masked, Multicenter, Exploratory Study of the Clinical Benefit and Safety of OMS302 Injection in Subjects Undergoing Unilateral Cataract Extraction With Lens Replacement (CELR) Using a Coaxial Phacoemulsification Process
This is an exploratory study to determine the safety and clinical benefit of OMS302 Injection in subjects undergoing Cataract Extraction with Lens Replacement (CELR) using a coaxial phacoemulsification process.
OMS302 Injection is a mydriatic/anti-inflammatory combination investigational drug product being developed as an irrigation solution during intracameral lens replacement surgical procedures of the eye. OMS302 irrigation solution may induce and maintain an adequately dilated pupil and reduce postoperative symptoms of discomfort such as eye pain and irritation. The use of OMS302 irrigation solution may eliminate the need for pre-operative dilation of the eye and could reduce the postoperative use of an anti-inflammatory and pain medications following surgery. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00924729 -
Study of Ocular Penetration of Topically Administered Fluoroquinolones
|
Phase 4 | |
Completed |
NCT00565695 -
Evaluation of the Aspheric ReSTOR Intraocular Lens (IOL) After Routine Cataract Extraction
|
N/A | |
Completed |
NCT00521456 -
A Study of Ketorolac for the Treatment of Inflammation and Pain Associated With Cataract Surgery
|
Phase 3 | |
Completed |
NCT00524264 -
A Study of Ketorolac for the Treatment of Inflammation and Pain Associated With Cataract Surgery
|
Phase 3 | |
Completed |
NCT02973880 -
Clinical Study to Evaluate the Efficacy and Tolerability of an Anti-inflammatory/Antibiotic Treatment Following Ocular Cataract Extraction
|
Phase 3 | |
Withdrawn |
NCT00466908 -
Accuracy of the Pentacam and IOL Master to Calculate the Effective Corneal Power After Corneal Refractive Surgery
|
||
Completed |
NCT00366665 -
Comparison of the Performance of the Infiniti Vision and the Series 20000 Legacy Phacoemulsification Systems
|
N/A | |
Completed |
NCT05571683 -
Cerebral Oxymeter and End Tidal Carbondioxide Values Under Surgical Drapes With and Without Past COVID-19 Infection
|
||
Not yet recruiting |
NCT04977115 -
Clinical Evaluation of Intraocular Caliper-assisted Capsulotomy for Age-related Cataract
|
N/A | |
Withdrawn |
NCT00366613 -
Clinical Evaluation of the Use of Sealed Capsule Irrigation With Sodium Chloride During Pediatric Cataract Surgery and IOL Implantation
|
Phase 4 | |
Completed |
NCT00366496 -
Surgical Outcomes After Routine Cataract Extraction & Implantation of a Conventional or Spheric Intraocular Lens
|
N/A | |
Not yet recruiting |
NCT03828500 -
Preoperative Fasting for Ambulatory Cataract Surgery: The PRACTICE Study
|
N/A | |
Completed |
NCT00840580 -
Effect on Wound Healing of Vigamox Versus Cravit
|
Phase 4 | |
Completed |
NCT00842231 -
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
|
N/A | |
Completed |
NCT00851760 -
Epiretinal Macular Membrane and Cataract Extraction
|
N/A | |
Recruiting |
NCT03944070 -
Management of Patients With Neovascular Age-related Macular Degeneration Undergoing Cataract Surgery
|
N/A | |
Completed |
NCT03364972 -
A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00
|
N/A | |
Completed |
NCT00824070 -
Assessment of the Concentrations of Besifloxacin, Moxifloxacin, or Gatifloxacin in the Aqueous Humor of Subjects
|
Phase 1 | |
Completed |
NCT00366691 -
Comparison of Acular LS With Lotemax to Prevent Inflammation After Cataract Surgery and Intraocular Lens Implantation
|
Phase 4 | |
Completed |
NCT00366587 -
Comparison of Visual Outcomes and Patient Satisfaction After Cataract Surgery and Implantation of ReSTOR and ReZoom IOLs
|
Phase 4 |