SSPC Evaluation on Carotid Artery Stenosis After Endarterectomy — SSPC  

Carotid Stenosis Clinical Trial

Official title: Multi-dimensional Evaluation of Carotid Artery Stenosis and Prediction of Brain Function After Endarterectomy by SSPC System

Status Recruiting

Clinical Trial Summary

SSPC includes degree of Stenosis, Symptoms, Plaque stability and Compensation of the cerebral blood flow. SSPC, a comprehensive evaluation system on carotid artery stenosis, is established and advocated in this trial in order to make assessment on risk of carotid revascularization preoperatively and prediction of cerebral events postoperatively.

Clinical Trial Description

Although, cerebral perfusion and collaterals recruitment are crucial and integral to current treatment and stroke prevention paradigms, most consensus recommendations do not include assessments of cerebral hemodynamics in their management algorithms and arbitrarily focus on symptoms and degree of stenosis.

Based on four aspects of SSPC multidimensional assessment and grading, through clinical data, specimen collection, image technology of the multi-disciplinary cross research, we initially to propose a more scientific evaluation system for the perioperative period of carotid revascularization, to reveal the scientific mechanism of brain function changes after carotid revascularization, and to establish a method for the evaluation of brain function after carotid revascularization in accordance with the characteristics of Chinese lesions. ;

Related Conditions & MeSH terms

• Carotid Artery Diseases
• Carotid Artery Plaque
• Carotid Stenosis
• Constriction, Pathologic

• NCT number: NCT05296876
• Study type: Observational [Patient Registry]
• Source: Shanghai Pudong Hospital
• Contact: Bo Yu, M.D.
• Phone: +8618918922698
• Email: paul.yubo@gmail.com
• Status: Recruiting
• Start date: April 1, 2022
• Completion date: November 30, 2023