Platelet Function and Neurological Events — MULTINEUR  

Stroke, Acute Clinical Trial

Official title: Platelet Function and Neurological Events Following Carotid Thromboendarterectomy

Status Recruiting

Clinical Trial Summary

Several studies have shown an association between platelet function and stroke in patients undergoing carotid thromboendarterectomy (TEA).

The present study will assess the correlation between platelet function evaluated by the impedance aggregometry and neurological events in patients undergoing carotid TEA.

Clinical Trial Description

Carotid thrombendarterectomy (TEA) is effective in preventing strokes which are a major cause of mortality and morbidity. Nevertheless, almost 10% of patients undergoing TEA develop a transient and/or permanent neurological injury. There is a growing body of evidence that platelet function is associated with perioperative neurological events in this setting, although the vast majority of patients undergoing carotid TEA are already on antiplatelet agents. The aim of the present study will be to assess the correlation between the platelet function evaluated by the impedance aggregometry (Multiplate ® Analyzer, Roche, Basel, Switzerland) and neurological events in patients undergoing carotid TEA. ;

Related Conditions & MeSH terms

• Carotid Artery Diseases
• Stroke
• Stroke, Acute

• NCT number: NCT05572320
• Study type: Observational
• Source: Scientific Institute San Raffaele
• Contact: Fabrizio Monaco, MD
• Phone: +39223467176
• Email: monaco.fabrizio@hsr.it
• Status: Recruiting
• Start date: October 10, 2022
• Completion date: September 20, 2025