Caries, Dental Clinical Trial
Official title:
Effectiveness of Pit and Fissure Sealants in the Prevention of Dental Caries
This randomized clinical trial is aimed at testing the efficacy of pit and fissure sealants, in a current environmental context different from that of the seventies and eighties. It has a split mouth design. 4OO subjects are included and the duration of follow up is 2 years.
This randomized clinical trial is aimed at testing the efficacy of pit and fissure sealants, in a current environmental context different from that of the seventies and eighties. This study assesses the cost-effectiveness of sealants according to the individual caries risk. This study takes place in Nice, Marseille and Paris (France) and the patients are to be enrolled both in the dental hospitals and in the private practice. In the hospitals, the subjects are recruited directly by the headmasters of the pediatric dentistry or public health departments in the three dental schools. In private practice, the head of the department of pediatric dentistry and / or public health dentistry, of each dental school chooses 4 to 6 private practitioners who are used to place dental sealants in their daily practice. They recruit the subjects among their own patients. The type of study corresponds to randomized clinical trial (Split mouth design) in which the tooth is the statistical unit (one pair of molars considered for each included patient). This study has a direct benefit for individuals. The number of necessary subjects is 328; the sample size is 400. The follow-up duration is 2 years. The treatment is a pit and fissure sealant on one randomized tooth by pair of permanent molars (Split mouth design). Sealant material is set up in accordance with the usual practice of each practitioner. Occlusal exams are conducted every 6 months. The effectiveness of dental sealants and the retention of sealing materials are statistically analyzed according to both the individual caries risk and the clinical protocol ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03119779 -
Effect of Pulpotomy Using TheraCal Versus MTA on Survival Rate of Cariously-Exposed Vital Permanent Molars
|
N/A | |
Completed |
NCT03004196 -
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
|
Phase 1/Phase 2 | |
Not yet recruiting |
NCT03590977 -
Efficacy of Licorice on Reducing Salivary Streptococcus Mutans Versus Chlorohexidine in Caries Risk Patients
|
N/A | |
Completed |
NCT03694496 -
The Effectiveness of an Oral Health Education Programme of Adolescents in Hong Kong
|
N/A | |
Completed |
NCT03412721 -
Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children
|
N/A | |
Completed |
NCT03552835 -
Management of Occlusal Dentinal Caries in Deciduous Molars
|
N/A | |
Completed |
NCT03426046 -
Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy
|
Phase 4 | |
Completed |
NCT00966394 -
Salivary Bacteria and Oral Health Status in Children With ADHD
|
N/A | |
Completed |
NCT03062605 -
Reducing Bacteria That Cause Tooth Decay
|
Phase 3 | |
Recruiting |
NCT03586713 -
Accuracy Of Sopro-Life Camera In Comparison With ICDAS II For Detection Of Initial Caries
|
N/A | |
Withdrawn |
NCT00973089 -
Alternative Treatment of Deep Carious Lesions Based on Biological Evidences
|
N/A | |
Not yet recruiting |
NCT05306691 -
Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients
|
Early Phase 1 | |
Completed |
NCT02333227 -
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi
|
N/A | |
Completed |
NCT03294590 -
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
|
N/A | |
Recruiting |
NCT03108313 -
Role of Aloe Vera Versus Fluoride Toothpaste in Changing High to Low Salivary Bacterial Count
|
Phase 2 | |
Active, not recruiting |
NCT02958891 -
Dental Health Epidemiology Among Israel Defense Forces (IDF) Recruits
|
N/A | |
Completed |
NCT03667768 -
Atraumatic Restorative Treatment Sealants in First Permanent Molars
|
N/A | |
Completed |
NCT03660410 -
Study of Oral Conditions in Indigenous Populations in the State of Roraima - Brazil
|
||
Completed |
NCT03078179 -
Effect of Lactobacillus Rhamnosus GG and Bifidobacterium Longum in Children Aged 3 to 5 Years of Villavicencio and Pasto
|
N/A | |
Completed |
NCT02494193 -
Indirect Pulp Capping With Resin Modified Glass Ionomer
|
N/A |