Clinical Trials Logo

Clinical Trial Summary

Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures ultimately resulting in improvised standard of patient care.

These bacteria metabolize different kind of carbohydrates accumulated around orthodontic appliances and create acidic environment in the oral cavity leading to enamel demineralization around the brackets and white spot lesions.

This study was carried out to evaluate and compare the efficacy of probiotic toothpaste and chlorhexidine mouthwash in patients undergoing orthodontic treatment with individuals who are not using them.


Clinical Trial Description

INTRODUCTION - When the basic oral hygiene is poor, orthodontic appliances create areas where plaque gets accumulated, especially around brackets, bands, wires, and other attachments; this facilitates the development of white spot lesions. Probiotics act by competitively inhibiting the pathogenic bacteria because they have greater adhesion to the tissues while Chlorhexidine is often used as an active ingredient in mouthwash designed to reduce dental plaque around orthodontic appliances. AIM & OBJECTIVE - The objectives of the study is to evaluate and compare the effects of the topical application of probiotic toothpaste and chlorhexidine mouthwash on the Streptococcus Mutans levels in the plaque of orthodontic patients hence improving the oral micro-flora of oral cavity by competitive inhibition of Streptococcus Mutans in plaque present around brackets.

MATERIAL & METHOD - The study consists of thirty randomly selected orthodontic patients undergoing fixed appliance treatment. The patients were divided into three groups - Control Group (Group 1), Probiotic Toothpaste Group (Group 2) & Chlorhexidine Mouthwash Group (Group 3). Samples were collected at two times interval: before the study began (Phase 1) and after thirty days (Phase 2). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03004196
Study type Interventional
Source Peoples University, Bhanpur, Bhopal
Contact
Status Completed
Phase Phase 1/Phase 2
Start date September 2015
Completion date October 2015

See also
  Status Clinical Trial Phase
Completed NCT03119779 - Effect of Pulpotomy Using TheraCal Versus MTA on Survival Rate of Cariously-Exposed Vital Permanent Molars N/A
Not yet recruiting NCT03590977 - Efficacy of Licorice on Reducing Salivary Streptococcus Mutans Versus Chlorohexidine in Caries Risk Patients N/A
Completed NCT03694496 - The Effectiveness of an Oral Health Education Programme of Adolescents in Hong Kong N/A
Completed NCT03412721 - Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children N/A
Completed NCT03552835 - Management of Occlusal Dentinal Caries in Deciduous Molars N/A
Completed NCT03426046 - Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy Phase 4
Completed NCT00966394 - Salivary Bacteria and Oral Health Status in Children With ADHD N/A
Completed NCT03062605 - Reducing Bacteria That Cause Tooth Decay Phase 3
Recruiting NCT03586713 - Accuracy Of Sopro-Life Camera In Comparison With ICDAS II For Detection Of Initial Caries N/A
Active, not recruiting NCT02333227 - Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi N/A
Withdrawn NCT00973089 - Alternative Treatment of Deep Carious Lesions Based on Biological Evidences N/A
Active, not recruiting NCT03294590 - Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children N/A
Recruiting NCT03108313 - Role of Aloe Vera Versus Fluoride Toothpaste in Changing High to Low Salivary Bacterial Count Phase 2
Active, not recruiting NCT02958891 - Dental Health Epidemiology Among Israel Defense Forces (IDF) Recruits N/A
Completed NCT03667768 - Atraumatic Restorative Treatment Sealants in First Permanent Molars N/A
Completed NCT03660410 - Study of Oral Conditions in Indigenous Populations in the State of Roraima - Brazil
Completed NCT03078179 - Effect of Lactobacillus Rhamnosus GG and Bifidobacterium Longum in Children Aged 3 to 5 Years of Villavicencio and Pasto N/A
Completed NCT02494193 - Indirect Pulp Capping With Resin Modified Glass Ionomer N/A
Completed NCT03872037 - Selective Dentine Removal in Primary Teeth N/A
Recruiting NCT03010618 - The Effects of Stainless Steel Crowns Applied With Hall Technique on Occlusal Vertical Dimension N/A