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NCT04977739 Clinical Trial

Research on the Application and Mechanism of New Biological Probes in Biomedicine

Cardiovascular Diseases Clinical Trial

Official title:
Research on the Application and Mechanism of New Biological Probes in Biomedicine

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04977739
Other study ID # NFEC-2021-007
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 3, 2021
Est. completion date July 25, 2022

Study information
Verified date June 2021
Source Nanfang Hospital of Southern Medical University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Fluorescence is one of the most commonly used research and detection techniques in the field of biomedical science. The characteristics of fluorescent probe directly affect the performance and application of fluorescence analysis and imaging. Aggregation-Caused Quenching has limited the application of traditional fluorescent probes to some extent. This project intends to systematically evaluate the detection efficiency of new methods through the detection of biomarkers in clinical samples and the comparison with the detection methods of traditional biomarkers, so as to provide theoretical and experimental basis for the establishment of fast and simple biomarker detection technologies with new biological probes.

Recruitment information / eligibility
Status Completed
Enrollment 737
Est. completion date July 25, 2022
Est. primary completion date July 15, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria: - Sign the informed consent form voluntarily. - Age 18-70 years old. - High expression (positive) group: The results of multiple laboratory tests indicate that the marker is higher than the normal range. - Low expression (negative) healthy volunteer group: those with no underlying diseases and no abnormalities in the physical examination. - Have routine examination to check the remaining body fluid samples, and the body fluid samples are not contaminated. Exclusion Criteria: - Accompanied by other inflammations. - The data of the subject is not complete, or the collection of cases is incomplete due to other reasons. - The researcher judged that it was not suitable to participate in this research.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• No intervention
No intervention

Locations
Country Name City State
China Nanfang Hospital Guangzhou Guangdong

Sponsors (1)
Lead Sponsor Collaborator
Nanfang Hospital of Southern Medical University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary signal intensity of the probes one day
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