Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence

Cardiovascular Diseases Clinical Trial

— PRESCRIBE  

Official title:

Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03021759
• Other study ID #: 826125
• Status: Completed
• Phase: N/A
• Start date: February 21, 2017
• Est. completion date: April 21, 2017

Study information

• Verified date: March 2019
• Source: University of Pennsylvania
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this study, the investigators will conduct a pragmatic, cluster-randomized, controlled trial to evaluate an active choice intervention with and without social comparison feedback to increase physician statin prescribing rates for eligible patients.

Description:

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States. Strong evidence indicates that statin medications can reduce the risk of CVD and for those with CVD statins have been shown to reduce mortality. Despite this evidence, statins are under-prescribed. In this study, the investigators will test the effectiveness of nudges targeted to physicians using active choice and social comparisons feedback to increasing the rate at which statin medications are prescribed to patients eligible based on national practice guidelines.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 4774
• Est. completion date: April 21, 2017
• Est. primary completion date: April 21, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 40 Years to 75 Years

Eligibility

Inclusion Criteria:

• Patient has a primary care physician at University of Pennsylvania Health System

• Patient meets 2013 AHA/ACC guidelines for statin therapy but no record of a statin prescription in the electronic health record

Exclusion Criteria:

• Patient has an allergy or adverse reaction to statins documented in the electronic health record

• Patient has glomerular filtration rate less than 30 mL/min

• Physicians (and their respective patients) will be excluded if they have less than 10 patients among their entire panel that are eligible for a statin

Related Conditions & MeSH terms

• Cardiovascular Diseases

Intervention

Behavioral:
• Active choice
Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin
• Social comparison feedback
Statin prescribing rates are communicated to physicians and along with how their performance compares to their peers

Locations

Country	Name	City	State
United States	University of Pennsylvania Health System	Philadelphia	Pennsylvania

Sponsors (1)

Lead Sponsor	Collaborator
University of Pennsylvania

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Statin Prescribing Rate	Percentage of patients eligible for a statin that have been prescribed a statin	Two Months