Epidemiology of Sudden Cardiac Arrest in Sub-Saharan Africa: Rationale and Design

Cardiovascular Diseases Clinical Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02142270
• Other study ID #: PASCAR
• Status: Not yet recruiting
• Phase: N/A
• First received: May 10, 2014
• Last updated: May 19, 2014
• Start date: January 2015
• Est. completion date: January 2018

Study information

• Verified date: May 2014
• Source: Cameroon Resuscitation Council
• Contact: Aime Bonny
• Phone: 33637975227
• Email: aimebonny[@]yahoo.fr
• Is FDA regulated: No
• Health authority: Cameroon: Ministry of Public Health
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Background The burden of sudden cardiac death (SCD) in Africa is unknown. Our aim is to assess the epidemiology of SCD in Africa. Methods The sub-Saharan Africa SCD study is a prospective, multicenter, community-based registry monitoring all cases of cardiac arrest occurring in victims > 15 years old. Investigators will use the definition of established SCD if an unexpected death without obvious extracardiac cause, occurred with a rapid witnessed collapse, or if unwitnessed, occurred within 1 hour after the onset of symptoms; probable SCD if an unexpected death without obvious extracardiac cause occurred within the previous 24 hours. After approval from institutional boards, Investigators will record demographic, clinical, electrocardiographic and biological variables of SCD victims (including survivors of cardiac arrest) in several sub-Saharan African cities. All deaths occurring in residents of districts of interest will be checked for past medical history, circumstances of death, and autopsy report (if possible). Investigators will also analyze the employment of resuscitation attempts during the timeframe of sudden cardiac arrest (SCA) in various patient populations throughout countries. Conclusion This study will provide comprehensive, contemporary data on the epidemiology of SCD in sub-Saharan Africa and will help in the development of strategies to prevent and manage cardiac arrest in this region of the world.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 250000
• Est. completion date: January 2018
• Est. primary completion date: January 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 15 Years and older

Eligibility

Inclusion Criteria:

• Victims of cardiac arrest, either SCD or aborted SCA

Exclusion Criteria:

• Age = 15 years.

• Refusal of consent (by the family).

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Cardiovascular Diseases

Locations

Country	Name	City	State
Cameroon	Bonny	Douala

Sponsors (1)

Lead Sponsor	Collaborator
Cameroon Resuscitation Council

Country where clinical trial is conducted

Cameroon, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Sudden Cardiac Death		3 years	No