Cardiovascular Diseases Clinical Trial
Official title:
Center for Advancing Equity in Clinical Preventive Services Project 2: Reducing Disparities in Primary Prevention of Cardiovascular Disease
Cardiovascular disease (CVD) is the leading cause of disparities in years of life lost by
race and low socioeconomic status. Statins have been shown to decrease the risk of
cardiovascular events among individuals with high CVD risk. Yet, despite increased statin
use and overall declining CVD rates, disparities in statin use and disparities in the
control of high cholesterol by race, ethnicity, and socioeconomic status have persisted.
Objective: To improve the appropriate use of statins for primary cardiovascular disease
prevention among high risk individuals at community health centers through a system of
population health management that uses electronic health record (EHR) data to identify
patients for targeted education and outreach.
Aim 1: Conduct a randomized controlled trial among individuals with 10-year risk for
myocardial infarction or coronary death of 10% or higher to determine if the population
health management intervention, compared to usual care, results in higher rates of
documented statin treatment discussions within 6 months (primary process outcome), higher
rates of statin prescribing within 6 months (secondary process outcome), and higher rates of
significant low-density lipoprotein cholesterol (LDL-C) lowering defined as a follow up
LDL-C ≥30 mg/dL lower than baseline (primary clinical outcome).
Aim 2: Interview patients who received the intervention to identify barriers to success
Aim 3: Assess the overall costs of the intervention and the costs per each patient who
achieves significant LDL-C lowering compared to patient who received usual care.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention
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