Cardiovascular Disease Clinical Trial
Official title:
Pilot Study to Evaluate the Effect of the Consumption of a Combination of Plant Extracts (BSL_EP025) on the Levels of LDL-cholesterol and Oxidized LDL-cholesterol in Healthy Volunteers
The objective of the study is to evaluate the ability of a combination of plant extracts (BSL_EP025) to reduce the levels of LDL-cholesterol and oxidized LDL-cholesterol in individuals with LDL-cholesterol levels between 100 and 190 mg/dL.
There is a strong relationship between serum cholesterol levels and cardiovascular diseases,
especially between coronary artery disease and LDL-cholesterol (LDL).
LDL is the lipoprotein responsible for delivering cholesterol to cells. However, in recent
years, special attention has been given to modified LDL, especially oxidized LDL, since it
plays a very important role in the initiation and progression of the atheroma plaque.
There are environmental and genetic factors that can influence the type and levels of blood
lipoproteins. Among the modulable factors (environmental) it has been observed that some
phytochemical compounds found in several plant extracts may reduce cardiovascular risk, due
to their antioxidant and anti-inflammatory properties.
The objective of the present study is to evaluate the possible effect of the intake of a
combination of plant extracts (BSL_EP025) on the levels of LDL-cholesterol and oxidized
LDL-cholesterol in healthy individuals with LDL-cholesterol levels between 100 and 190 mg/dL.
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