Correlation Between Epistaxis and Cardiovascular Disease

Cardiovascular Disease Clinical Trial

— CBECD  

Official title:

Epistaxis Correlate With Cardiovascular Disease?

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02677467
• Other study ID #: Gurivengers
• Status: Not yet recruiting
• Phase: N/A
• First received: January 31, 2016
• Last updated: February 8, 2016
• Start date: March 2016
• Est. completion date: August 2016

Study information

• Verified date: February 2016
• Source: Hanyang University
• Contact: YOONJE LEE, M.D.
• Phone: +82-31_560-2053
• Email: yong0831[@]naver.com
• Is FDA regulated: No
• Health authority: Korea: Institutional Review Board
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Investigators examine blood-pressure variance, several cardiovascular risk factors of patient with epistaxis. As a result of collected data, investigators look into correlation between epistaxis and hypertensive cardiovascular disorder.

Description:

This study is prospective observational single blinded study.

A participant is visit in the ER who patient with epistaxis.

Investigators will enroll 50 patients with epistaxis. Exclusion criteria is that patient needs immediately treatment for hypertensive urgency or patient with nasal trauma.

Investigators examine blood-pressure (BP) at five times in Emergency Department (ED) and out-patient department (opd) of Otorhinolaryngology (OL) . Investigators explain this study and ask to write consent for participant. After proper management of epistaxis, investigators get blood sampling of the participant and, the participant has a reservation to "opd of cardiovascular division of Internal Medicine" (CV opd) in the hospital.

When the participant visit CV opd, the participant undergo 24-hours-BP-monitoring and Pulse wave velocity (PWV).

After that, the participant will be follow-up for 3 months.

Investigators collect 50 data from 50 participants as a registry and analyze the data.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: August 2016
• Est. primary completion date: June 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Group A

Inclusion Criteria:

• age is over 18 with spontaneous epistaxis

Exclusion Criteria:

• they needs immediately treatment for hypertensive urgency.

• they don't want to participate in this investigation.

Group B

Inclusion Criteria:

• age is over 18 with bleeding of wound

Exclusion Criteria:

• their wounds' condition is serious or their pain is much severe.

• they don't want to participate in this investigation.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Cardiovascular Disease
• Cardiovascular Diseases
• Epistaxis

Intervention

Biological:
• Blood-pressure variability
Day to Night Blood pressure variability

Locations

Country	Name	City	State
Korea, Republic of	Hanyang University Guri Hospital	Guri-si	Gyeonggi-do

Sponsors (1)

Lead Sponsor	Collaborator
Hanyang University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cholesterol level in each group		1 day	Yes
Primary	BP variability level in each group		1 day	Yes
Primary	Pulse wave velocity in each group		1 day	Yes
Secondary	Smoking History in each group	Example = "12 pack-year"	1 day	Yes
Secondary	Body Mass Index in each group		1 day	Yes