Effect of Pumpkin Seeds on the Dietary Fatty Acid Intake and Blood Pressure in Women

Cardiovascular Disease Clinical Trial

— PSS1  

Official title:

Effect of Pumpkin Seeds on the Dietary Fatty Acid Intake and Blood Pressure in Women

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT01928966
• Other study ID #: TWU-1PS
• Status: Withdrawn
• Phase: N/A
• First received: August 21, 2013
• Last updated: May 24, 2017
• Start date: August 2013
• Est. completion date: November 2014

Study information

• Verified date: May 2017
• Source: Texas Woman's University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine if the inclusion of 1.5 ounces of pumpkin seeds per day in the diet of women will alter dietary fatty acid intake or blood pressure.

Description:

Cardiovascular disease is the number one cause of morbidity and mortality in United States. Diets high in polyunsaturated and monounsaturated fatty acids have been shown to decrease the risk of cardiovascular disease. Pumpkin seeds are a good source of monounsaturated and polyunsaturated fatty acids. Oil extracted from pumpkin seeds has been shown to lower blood pressure. One purpose of this study is to determine whether eating 1.5 ounces of pumpkin seeds per day will improve polyunsaturated and monounsaturated fatty acid intake in the diet in healthy adult women. Another purpose of this study is to determine whether eating 1.5 ounces of pumpkin seeds a day will lower blood pressure.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: November 2014
• Est. primary completion date: November 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Female

• Over the age of 18

• Able to read, write, and speak English

• Able to keep a three-day diet diary

• Willing and able to consume pumpkin seeds

Exclusion Criteria:

• Pregnant or planning to become pregnant

• Allergic to pumpkin seeds

• High blood pressure

• Regularly consuming pumpkin seeds (more than 4 times per month)

• Taking blood pressure medication

• Liver disease

• Kidney disease

• Gastrointestinal disease

• History of bariatric surgery

• History of a major cardiovascular event

• Heart disease

• Currently undergoing cancer treatment (except nonmelanoma cancer)

• Following a weight control diet

• Following a disease specific diet

• Following a vegan diet

• Have a diagnosed eating disorder

Related Conditions & MeSH terms

• Blood Pressure
• Cardiovascular Disease
• Cardiovascular Diseases

Intervention

Other:
• Pumpkin Seeds
Participants will be asked to consume 1.5 ounces of raw, unsalted pumpkin seeds per day. The 1.5 ounces will be split in to two servings (each 0.75 ounces).

Locations

Country	Name	City	State
United States	Texas Woman's University	Houston	Texas

Sponsors (1)

Lead Sponsor	Collaborator
Texas Woman's University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Dietary fatty acid intake	The dietary fatty acid intake, specifically monounsaturated and polyunsaturated fatty acids, will be measured three times over the course of a twelve week period to determine if fatty acid intake changed during the intervention.	12 weeks
Primary	Blood pressure	Blood pressure will be measured at every meeting to determine if the addition of pumpkin seeds to the diet altered blood pressure.	12 weeks