Gene - Exercise Research Study

Cardiovascular Disease Risk Factors Clinical Trial

— GERS  

Official title:

Impact of Common Genetic Polymorphisms on CV Disease Risk Factor Changes With Endurance Exercise Training

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00976742
• Other study ID #: AG17474
• Status: Completed
• Phase: N/A
• First received: September 11, 2009
• Last updated: September 11, 2009
• Start date: June 1998

Study information

• Verified date: September 2009
• Source: University of Maryland
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The investigators hypothesize that the degree to which older generally healthy but sedentary men and women improve a number of cardiovascular (CV) disease risk factors with 6 months of highly-standardized endurance exercise training will be a function of common genetic variations in candidate genes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 225
• Est. primary completion date: December 2004
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 50 Years to 75 Years

Eligibility

Inclusion Criteria:

• generally healthy

• free from CV disease

• ability to undergo exercise training

Exclusion Criteria:

• previous history of CV disease

Study Design

Intervention Model: Single Group Assignment, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Cardiovascular Disease Risk Factors
• Cardiovascular Diseases

Intervention

Behavioral:
• Endurance exercise training

Locations

Country	Name	City	State
United States	University of Maryland Dept of Kinesiology	College Park	Maryland

Sponsors (2)

Lead Sponsor	Collaborator
University of Maryland	University of Pittsburgh

Country where clinical trial is conducted

United States, 

References & Publications (1)

Halverstadt A, Phares DA, Wilund KR, Goldberg AP, Hagberg JM. Endurance exercise training raises high-density lipoprotein cholesterol and lowers small low-density lipoprotein and very low-density lipoprotein independent of body fat phenotypes in older men — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cardiovascular Disease Risk Factors		~9 months	No