Cardiovascular Disease Clinical Trial
Official title:
PILOT-EBM: Patient Focused Intervention to Improve Long-term Adherence to Evidence Based Medications
The purpose of this study is to evaluate the effectiveness of a program to help patients with heart disease stay on their heart medications.
Heart disease is the leading cause of death for men and women in the United States. For
patients with documented coronary artery disease (CAD), anti-platelet agents, beta-blockers
and statins have all been shown to improve survival and reduce the frequency of myocardial
infarction. Yet, previous research by the Duke CERTs has shown that in a population of over
28,000 patients with documented CAD, only 21% reported consistent use of triple therapy with
aspirin, beta-blockers and lipid lowering therapy. These results stimulated the Duke CERTs
to devise an intervention to improve adherence to these life-saving medications.
Comparisons: Patients admitted to Duke University Hospital or Southeastern Regional Medical
Center (SRMC) with CAD or CAD plus heart failure who agree to participate, will be
randomized to an intervention or control arm. The control group will receive usual care,
which consists of routine discharge counseling performed by the patient-care nurse and a
letter/discharge summary from the Duke physician to the community physician. In addition to
usual care, the intervention group will receive focused medication counseling in the
hospital by the clinical pharmacist-investigator, who will identify and address potential
barriers to medication adherence and will reinforce the importance of taking evidence-based
medications long term. Discharge medications will be shared with the community pharmacist.
The community pharmacist will monitor for problems with adherence and communicate issues
back to the patient and the patient's care team.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor)
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