Novel Cardiac Pacing to Initiate Cardiac Remodeling in Heart Failure

Status Completed

Clinical Trial Summary

This project utilizes a novel cardiac pacing approach hypothesized to initiate beneficial cardiac conditioning and remodeling over a period of time.

Clinical Trial Description

The project studies subjects with non-ischemic cardiomyopathy who have a pacing device already implanted. Subjects randomized to the pacing intervention versus a sham intervention will be compared for various symptomatic, functional and other outcomes. Each subject will undergo baseline quality of life/symptom questionnaires and clinical testing for cardiac functional/structural effects and exercise tolerance, then the intervention vs. sham (subjects blinded to their category), followed by repeat questionnaires and clinical testing. Medical record review will be undertaken to establish demographic variables, baseline and follow up testing results. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05600725
Study type	Interventional
Source	University of Iowa
Contact
Status	Completed
Phase	N/A
Start date	November 2, 2022
Completion date	February 28, 2023

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