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Cardiac Surgery clinical trials

View clinical trials related to Cardiac Surgery.

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NCT ID: NCT05853731 Withdrawn - Cardiac Surgery Clinical Trials

The Effect of Light Therapy on Post-Surgical Pain

Start date: December 2023
Phase: N/A
Study type: Interventional

Researchers aim to demonstrate that the use of phototherapy is feasible and may reduce acute postoperative pain based on recent literature. The primary objective is to demonstrate that displaying light-emitting diodes [LED] can be achieved in the ICU setting in after cardiac surgery.

NCT ID: NCT05634213 Withdrawn - Cardiac Surgery Clinical Trials

Feasibility of Transepicardial Atrial Injection

Start date: March 1, 2023
Phase: Early Phase 1
Study type: Interventional

Single blind feasibility trial using a binary 'traffic light' design to evaluate the feasibility of injecting normal physiological saline into the atria of patients at the time of clinically indicated open chest cardiac surgery.

NCT ID: NCT04678726 Withdrawn - Cardiac Surgery Clinical Trials

Nurse-performed Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax.

Start date: July 2023
Phase:
Study type: Observational

This is a prospective, single-center, observational, cross-sectional cohort study, comparing nurse-performed bedside lung ultrasound to standard portable CXR, for the detection of pneumothorax in the cardiac surgery patient population, following chest tube removal. This study aims to be conducted at an academic, tertiary adult center cardio-vascular intensive care unit (CVICU at TGH).

NCT ID: NCT04432337 Withdrawn - Type 2 Diabetes Clinical Trials

Role of Type 2 Diabetes in Potentiating the Inflammatory Response Post Extracorporeal Circulation After Cardiac Surgery

DT2CEC
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Adult cardiac surgery ensures the surgical treatment of valvular and coronary pathologies and of heart failure with the placement of ventricular assistance. Extracorporeal circulation (ECC) is one of the major technical advances associated with cardiac surgery to replace cardiac and pulmonary functions during surgery. ECC can nevertheless lead to postoperative complications, the origin of which is linked to the patient's initial contact with the circuit and membranes of the ECC. This contact triggers a series of humoral and cellular reactions that occur in the first few hours after the ECC and the inflammatory syndrome post ECC fades on its own and usually disappears between the 4th and 6th postoperative day. If the inflammatory response post ECC is most often transient, certain conditions will maintain and intensify this response at the origin of postoperative complications, possibly leading to the patient's death. Among these situations, the investigators find the notion of emergency cardiac surgery, a patient's age over 75 years and a preoperative history of decompensated heart failure, renal failure or type 2 diabetes (T2D). The inflammasome family of receptors of the nucleotide oligomerization domain (NOD) type, pyrin domain containing 3, NLRP3, is a multi-protein platform of recent discovery which plays a major role in the signaling pathways of the innate inflammatory response. The role of the activation of the NLRP3 inflammasome in cardiovascular pathologies is now well established and its metabolic priming by hyperglycemia could explain the greater seriousness of these pathologies in T2D patients due to an exacerbated inflammatory response. What is the effect of T2D status on the inflammatory response post ECC, mediated by the NLRP3 inflammasome, in patients after cardiac surgery?

NCT ID: NCT04348981 Withdrawn - Cardiac Surgery Clinical Trials

Preventing Cardiac Surgery Readmission With Patient Activity Tracking Technology

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to detect decreased patient activity level after discharge after cardiac surgery to prevent readmissions. Cardiac surgery is associated with a high chance of readmission within 30 days, common reasons being volume overload, arrhythmia, pulmonary complications, and infections. A decreased activity level often precedes those complications. Measuring patient activity levels using wearable activity trackers (Fitbit) may detect complications early and prompts the surgical team to contact the patient before a visit to the Emergency Room is warranted.

NCT ID: NCT04282239 Withdrawn - Pain, Postoperative Clinical Trials

Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine if the addition of PECS2 block provides superior post-operative analgesia for cardiac surgery patients after midline sternotomy compared to only standard-of-care post-operative pain medication.

NCT ID: NCT03954002 Withdrawn - Cardiac Surgery Clinical Trials

Quantification of Right Ventricular Function Using Simultaneous Transthoracic and Transoesophageal Echocardiography

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

The aims of this study are to evaluate the usefulness of various methods of quantifying right ventricular (RV) function using perioperative transoesophageal echocardiographic (TOE), compared with simultaneous transthoracic echocardiographic (TTE) findings.

NCT ID: NCT03947671 Withdrawn - Cardiac Surgery Clinical Trials

Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction

Start date: January 22, 2020
Phase: Phase 2
Study type: Interventional

This study will assess the effect of active postoperative temperature management and its effect on the cognitive function in patients following coronary artery bypass graft (CABG) surgery to determine if active postoperative temperature management to maintain normothermia reduces postoperative cognitive dysfunction (POCD) in this population. Additionally, the investigators will explore differences in temperature control variability by using temperature management wraps combined with acetaminophen vs. acetaminophen alone in a pilot arm.

NCT ID: NCT03784690 Withdrawn - Cardiac Surgery Clinical Trials

Individualized Blood Pressure Management in Patients Undergoing Cardiac Surgery

PRECISE
Start date: January 21, 2019
Phase: N/A
Study type: Interventional

This pilot randomized-controlled study will determine the feasibility of large study comparing individualized versus standard blood pressure (BP) management in patients undergoing cardiac surgery under cardiopulmonary bypass (CPB). Our hypothesis is that maintaining higher BP levels based on preoperative measurements will reduce the incidence of major complications (composite outcome).

NCT ID: NCT03390543 Withdrawn - Cardiac Surgery Clinical Trials

The Effect of Simple Needle Guide Device for Ultrasound-guided Internal Jugular Vein Catheterization in Cardiac Surgical Patients

Start date: January 17, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of simple needle guide device for ultrasound-guided internal jugular vein catheterization in cardiac surgical patients